A Review of Chalcones: Synthesis, Reactions, and Biological Importance | ||
| Egyptian Journal of Chemistry | ||
| Article 35, Volume 65, Issue 8, August 2022, Pages 379-395 PDF (483 K) | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2022.112735.5125 | ||
| Authors | ||
| Shorouk S. Mukhtar1; Nesrin M. Morsy* 2; Ashraf S. Hassan3; Taghrid S. Hafez4; Hamdi M. Hassaneen5; Fatma M. Saleh5 | ||
| 1Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Dokki 12622, Egypt | ||
| 2Organometallic and Organometalloid Chemistry Department,National Research Centre | ||
| 3Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki 12622, Cairo, Egypt | ||
| 4Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki 12622 Cairo, Egypt | ||
| 5Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt | ||
| Abstract | ||
| Chalcones are considered an important scaffold in organic compounds. Many of their derivatives have a lot of applications. Therefore, this review was covered some synthesis methods of chalcones such as Claisen-Schmidt’s condensation, coupling reaction, continuous-flow deuteration reaction, and other reactions. Also, some reactions were discussed such as the synthesis of seven, six, and five-membered ring heterocyclic compounds. Moreover, some of their biological applications were mentioned like antimicrobial, anticancer, anti-inflammatory, antioxidants, and others with some details. | ||
| Keywords | ||
| Chalcones; Synthesis; Reactions; Biological applications | ||
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