THE USE OF BIOMARKERS TO PREDICT ATTACKS OF SEVERE BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE | ||
| Journal of Environmental Science | ||
| Article 38, Volume 50, Issue 12, December 2021, Pages 1-25 PDF (577.88 K) | ||
| Document Type: Review Article | ||
| DOI: 10.21608/jes.2022.92936.1060 | ||
| Authors | ||
| Mahmoud A. El-Shourbagy* 1; Mahmoud S. El Bokhary1; Hewaida M. Kamal2 | ||
| 1Faculty of Graduate Studies and Environmental Research, Ain Shams University | ||
| 2Department of Clinical and Chemical Pathology, Faculty of Medicine, Banha University | ||
| Abstract | ||
| Introduction: Increased levels of C-reactive protein (CRP) and fibrinogen among asthmatic and Chronic Obstructive Pulmonary Disease (COPD) patients were associated with disease severity and complications. Aim of the work: To assess the possible relationship between selected variables and hospitalization as unfavorable outcome. Subjects and methods: 172 subjects had participated in this observational study and grouped into three groups; control, asthmatic and COPD. Blood analysis used for fibrinogen and CRP levels and pulmonary function were measured. Statistical analysis using t-test, ROC, and regression test in order to assess the predictive potential of those variables. Results: mean of fibrinogen among COPD group (583.24 mg/dL) was significantly higher than control (207 mg/dL), (P | ||
| Keywords | ||
| Asthma; COPD; CRP; Fibrinogen | ||
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