Role of Hypochromia and Microcytosis in theprediction of iron deficiency anemia | ||
Minia Journal of Medical Research | ||
Volume 31, Issue 3, July 2020, Pages 262-268 PDF (291.92 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/mjmr.2022.220289 | ||
Authors | ||
Shimaa G. Mohammed1; Abdel . Hamead M Mousa1; Alaa M. Hashim2 | ||
1Department of Clinical pathology, Al-Azhar University, Faculty of Medicine (Assiut). | ||
2Department of Clinical pathology, Al-Azhar University, Faculty of Medicine (Assiut) | ||
Abstract | ||
Objective: The present study aimed at assessing the role of hypochromia and microcytosis in the determination of iron storage state and early detection of iron deficiency anemia (IDA). Background: Anemia is defined as hemoglobin (Hb) concentration below the reference range (Hb level below 13 g/dl in men, 12 g/dl in women, and 11g/dl in pregnant women and preschool children). The assessment of hypochromia and microcytosis can help more prediction of (IDA). Patients and methods: This study included 60 patients with normal Hb levels with decreased Mean Corpuscular Volume (MCV) & Mean Corpuscular Hemoglobin (MCH) and 30 healthy subjects as a control group. All patients were subjected to history taking, clinical examinations, laboratory investigations such as Complete blood count (CBC), serum iron, serum ferritin (SF), total iron-binding capacity (TIBC), C - reactive protein (CRP) and Hb. Electrophoresis. Results: Mean MCV, MCH, Serum iron, SF, TIBC, CRP, and Hb. Electrophoresis had statistically significant difference between the two groups (p-value <0.0001). Conclusion: It indicates an early sign of (IDA). Abbreviations: IDA; iron deficiency anemia, Hb; hemoglobin, MCV; Mean Corpuscular Volume, MCH; Mean Corpuscular Hemoglobin, CBC; Complete blood count, SF; serum ferritin, TIBC; total iron-binding capacity and CRP; C - reactive protein. | ||
Keywords | ||
Anemia; hypochromia; and microcytosis | ||
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