Stripping Voltammetric Determination of L-dopa using Poly Sulfacetamide Modified Glassy Carbon Electrode | ||
| Assiut University Journal of Multidisciplinary Scientific Research | ||
| Volume 45, Issue 2, December 2016, Pages 87-98 PDF (653.19 K) | ||
| Document Type: Novel Research Articles | ||
| DOI: 10.21608/aunj.2016.221439 | ||
| Abstract | ||
| The voltammetric behavior of L-dopa was studied at poly sulfacetamide modified glassy carbon electrode (SFA-modified GCE), based on electrochemical oxidation of sulfacetamide. The modified electrode exhibited good selectivity and strong electrocatalytic activity for electrochemical oxidation of L-dopa in Britton – Robinson buffer solution (pH 2). Under the chosen conditions, the oxidation peak currents showed a linear dependence on the L-dopa concentration in the range of 1×10-7 to 1.1×10-6M with limit of detection of 0.3×10-9 M. This method was applied to the determination of L-dopa in human serum and urine with satisfactory results. In addition, L-dopa was determined in presence of ascorbic acid (AA), uric acid (UA) and glucose. | ||
| Keywords | ||
| Stripping voltammetry; L-dopa; Sulfacetamide; Ascorbic acid; Uric acid | ||
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