Efficacy of thyroid isthmusectomy and its outcomes in patients with single isthmic papillary thyroid carcinoma: a single-center observational study | ||
| Minia Journal of Medical Research | ||
| Article 33, Volume 30, Issue 4, October 2019, Pages 198-205 PDF (348.53 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2022.221716 | ||
| Authors | ||
| Ahmed Elsayed Mohamed1; Alsayed Basiony Moghazy2 | ||
| 1Department of Surgical Oncology, Faculty of Medicine, Al-Azhar University, Cairo Egypt. | ||
| 2Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| Background; Despite the total thyroidectomy is recommended for isthmic papillary thyroid carcinoma (PTC), the gold standard surgery is not well-known. We aimed to investigate the efficacy of isthmusectomy and its outcomes in the treatment of isthmic PTC. Methods; All patients with single isthmic PTC and underwent total thyroidectomy with or without central neck dissection (CND) were included in the study. Patients with cervical lymph node metastasis and neck extension or patients with their cancer in another place were omitted from the study. Included patients were subdivide into 3 groups; total thyroidectomy, lobectomy with isthmusectomy, and isthmusectomy. Clinical and pathologic data and surgical outcomes were collected. Results: Among the included 121 patients, 28 were males and 93 were females. Total thyroidectomy, isthmusectomy, and lobectomy with isthmusectomy were conducted in 70 (57.8%), 11 (9.1%), and 40 (33.1%), patients, respectively. Patients with total thyroidectomy showed increased postoperative hypoparathyroidism than patients with lobectomy and isthmusectomy. On the other hand, there were no significant differences in the recurrence rate or the survival between the 3 groups. Conclusion; Total thyroid isthmusectomy may be helpful in the surgical management of small single isthmic PTC. Further studies are needed to verify this result. | ||
| Keywords | ||
| Isthmusectomy; Papillary thyroid carcinoma | ||
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