Occlusion of Dentinal Tubules Using a Novel Dentifrice with Fluoro-Hydroxyapatite Nanoparticles Derived From A Biologic Source. (an in vitro study)
Diab, M., Habib, A., El korashy, S., Badawy, R. (2022). Occlusion of Dentinal Tubules Using a Novel Dentifrice with Fluoro-Hydroxyapatite Nanoparticles Derived From A Biologic Source. (an in vitro study). EKB Journal Management System, 3(1), 39-44. doi: 10.21608/dsu.2022.91237.1078
Maha Diab; Ahmed Habib; Sabri El korashy; Rania Badawy. "Occlusion of Dentinal Tubules Using a Novel Dentifrice with Fluoro-Hydroxyapatite Nanoparticles Derived From A Biologic Source. (an in vitro study)". EKB Journal Management System, 3, 1, 2022, 39-44. doi: 10.21608/dsu.2022.91237.1078
Diab, M., Habib, A., El korashy, S., Badawy, R. (2022). 'Occlusion of Dentinal Tubules Using a Novel Dentifrice with Fluoro-Hydroxyapatite Nanoparticles Derived From A Biologic Source. (an in vitro study)', EKB Journal Management System, 3(1), pp. 39-44. doi: 10.21608/dsu.2022.91237.1078
Diab, M., Habib, A., El korashy, S., Badawy, R. Occlusion of Dentinal Tubules Using a Novel Dentifrice with Fluoro-Hydroxyapatite Nanoparticles Derived From A Biologic Source. (an in vitro study). EKB Journal Management System, 2022; 3(1): 39-44. doi: 10.21608/dsu.2022.91237.1078

Occlusion of Dentinal Tubules Using a Novel Dentifrice with Fluoro-Hydroxyapatite Nanoparticles Derived From A Biologic Source. (an in vitro study)

Dental Science Updates
Article 6, Volume 3, Issue 1, March 2022, Pages 39-44    PDF (587.93 K)
Document Type: Original Article
DOI: 10.21608/dsu.2022.91237.1078
Authors
Maha Diab* 1; Ahmed Habib2; Sabri El korashy3; Rania Badawy4
1Dental Materials Department, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.
2Dental materials department, Faculty of dentistry, Cairo university, Cairo, Egypt.
3Inorganic chemistry department, Faculty of science, Suez canal university,Ismailia, Egypt.
4Dental Material Department-Faculty of Dentistry-Suez-Canal University
Abstract
Introduction: Dentin hypersensitivity is a widespread issue with high prevalence.
Blocking the open dentinal tubules is one way to reduce dentin hypersensitivity.
Aim: The current study aimed at evaluating the in vitro potential of a novel experimental
dentifrice made of nano-fluoro hydroxyapatite (n-FHAP) produced from a biogenic
source (cuttlefishbones) for occlusion of dentinal tubules. Material and Methods: 30
dentin discs (n = 30) were classified into 3 categories (n = 10) based on the dentifrices
they utilized for brushing: 1st category = artificial saliva (AS; control); 2nd category
= fluoride dentifrice (Sensodyne, UK); 3rd category = experimental nano-FHAP dentifrice.
Then, after brushing, discs were subjected to an acidic challenge with 6 percent
wt citric acid (pH = 4.0) for 1 minute. By utilizing a SEM (scanning electron
microscope) and EDX (energy-dispersive X-ray) spectroscopy before and after the
citric acid challenge, the tubule occlusion was measured. Results: Group 1 (AS) SE
micrographs revealed no tubule blockage. The tubules in Groups 2 and 3 were mostly
blocked, according to SE micrographs. Data before and after the citric acid challenge
data were statistically significant (p= 0.05) for all groups. Conclusion: In terms of tubule
blockage, the findings of the new experimental dentifrice were equivalent to those
of Sensodyne. Dentifrice containing FHAP nano-particles might be used to treat dentin
sensitivity as an alternative.
Keywords
Dentin; FHAP; Occlusion; Toothpaste
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