The value of Serum Amyloid A in Preeclampsia | ||
| Al-Azhar University Journal of Medical and Virus Researches and Studies | ||
| Article 4, Volume 4, Issue 1, March 2022, Pages 29-39 PDF (523.31 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aujv.2022.222824 | ||
| Abstract | ||
| Preeclampsia is a common complication of pregnancy and remains a common cause of maternal and fetal mortality. The clinical symptoms of preeclampsia are caused by widespread endothelial dysfunction suggested to be a part of an exaggerated maternal inflammatory response to pregnancy. The objective of this study is to estimate serum amyloid A in pregnant women with preeclampsia. Type of study: Case control study. Study period: from Septemper2019 to August 2021. Study population: The study was carried out on 75 women divided into three groups: Group I (25 women): The control group are healthy pregnant women who had an uncomplicated antenatal course. Group II (25 women): They are women with mild preeclampsia. Group III (25 women): They are women with severe preeclampsia. Serum amyloid A level (SAA) varied significantly in severe preeclampsia compared to mild and control groups. There was statistically significant positive correlation between serum amyloid A level and most of the indices of severity of preeclampsia, including systolic and diastolic blood pressure, liver transaminases, serum creatinine and albuminuria. | ||
| Keywords | ||
| Angiotensin receptor; Extravillous trophoblast; Serum amyloid A | ||
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