Relation Between Serum Eotaxin and Carotid Intima-Media Thickness in Obese Patients With Non Alcoholic Fatty Liver and Hepatitis C Virus Patients. | ||||
Minia Journal of Medical Research | ||||
Volume 30, Issue 1, March 2019, Page 194-197 PDF (101.68 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2022.222890 | ||||
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Authors | ||||
Mohammed A. Sharawy; Mohamed E. Abd El Aal Shatat; Emad A. Abd AlNaeem; Al Shmaa A. Mohamad | ||||
Department of Internal Medicine, El-Minia Faculty of Medicine | ||||
Abstract | ||||
Chronic hepatitis C (CHC) is a leading cause of chronic hepatitis, cirrhosis, liver failure,and hepatocellular carcinoma world wide. Aim of the Work: Is to evaluate the relation between serum eotaxin and carotid intima-media thickness hn obese patients with nonalcoholic fatty liver and hepatitis c virus patients. Patient and Methods: This prospective study was carried out in department of internal medicine, Minia university hospital,80 persons were studied. The study protocol was approved by the institutional ethics committee of school of medicine, minia university. Results: The study included 80 subjects subdivided into: Twenty obese patients considered as group-1. Twenty patients with chronic hepatitis C virus (without treatment by combined interferon and ribavirin); considered as group-2. Twenty patients with chronic hepatitis C virus who was treated by combined interferon and ribavirin and had-ve pcr for HCV RNA; considered as group-3. Discussion: Hepatitis C virus (Hcv) is a leading cause of chronic hepatitis, cirrhosis, liver failure, and hepatocellular carcinoma worldwide. Conclusion & Recommendation : our study suggests that serum eotaxin level could be a good predictor for NAFLD; and response for anti-HCV .treatment. Also, our study recommends further studying of serum eotaxin levels and other chemokines, to clarify their role in CHC and NAFLD. | ||||
Keywords | ||||
alanine aminotransferase; bovine serum albumin; intima media thickness | ||||
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