Fractional CO2 Laser versus Gycolic Acid and Topical Tretinoin in the Treatment of Macular Amyloidosis: A Comparative Study | ||||
| The Medical Journal of Cairo University | ||||
| Article 86, Volume 89, December, December 2021, Page 2949-2952 PDF (286.4 K) | ||||
| DOI: 10.21608/mjcu.2021.225238 | ||||
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| Authors | ||||
| NAGLAA S. ZAKI, M.D.; DINA M. EL-GHAYATI, M.Sc.; SOLWAN I. EL-SAMANOUDY, M.D.; MARWA S. EL-MESIDY, M.D. | ||||
| The Department of Dermatology, Faculty of Medicine, Cairo University | ||||
| Abstract | ||||
| Abstract Background: Macular amyloidosis (MA) is a variant of primary localized cutaneous amyloidosis. Several modalities were used to treat macular amyloidosis with variable results. Aim of Study: To compare the efficacy of fractional CO2 laser versus glycolic acid peeling with topical tretinoin appli-cation in treating macular amyloidosis. Patients and Methods: Twenty five female patients with macular amyloidosis aged between 19-59 years were treated by 4 sessions of fractional CO2 laser on the right side and Glycolic acid (20%) peeling and topical tretinoin 0.025% cream in between the sessions on the left side at 3-week intervals. Clinical improvement in terms of global improvement score was evaluated. Satisfaction grade was also assessed. Results: Both areas showed significant increase in the global improvement scale without significant difference between both areas. Conclusion: Both fractional CO2 Laser and glycolic acid peeling with application of topical tretinoin in between the sessions are effective in the treatment of macular amyloidosis. | ||||
| Keywords | ||||
| Fractional CO2 laser; Macular amyloidosis; Glycolic acid; Topical tretinoin | ||||
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