Serum Level of Vitamin B12 in Patients with Vitiligo and its Potential Role as a Disease Biomarker | ||
The Medical Journal of Cairo University | ||
Article 87, Volume 89, December, December 2021, Pages 2953-2958 PDF (214 K) | ||
DOI: 10.21608/mjcu.2021.225244 | ||
Authors | ||
MAHA A. ELMESELLAWY. M.Sc.; HANAN M. SALEH. M.D.; MARWA Y. AHMED, M.D. | ||
The Department of Dermatology, Venerology and Andrology, Faculty of Medicine, Ain Shams University | ||
Abstract | ||
Abstract Background: Vitiligo is an acquired depigmenting cuta-neous disorder characterized by the loss of melanocytes from the epidermis. It affects approximately 0.5% of the population worldwide. Aim of Study: To determine serum vitamin B 12 level in patients with vitiligo and healthy controls to determine its possible role as a disease biomarker. Patients and Methods: This study was conducted on 40 patients with vitiligo and 40 age and sex matched healthy controls recruited from El-Demerdash Hospital, Ain Shams University. Results: Serum level of vitamin B12 decreased in cases in comparison to control, and there is an inverse relation between vitamin B 12 and affected body parts. Conclusion: This study confirms that vitamin B12 is a very efficient and simple biomarker for vitiligo cases. Thus we recommended the use of vitamin B 12 in investigation to improve our diagnostic capabilities in vitiligo patients. | ||
Keywords | ||
Serum vitamin B12; Vitiligo; Disease biomarker | ||
Statistics Article View: 410 PDF Download: 2,833 |