Study of Prevalence of Autoimmune Manifestations of Chronic Hepatitis C Infection in Beni-Suef Governorate | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 125, Volume 87, Issue 1, April 2022, Page 1736-1742 PDF (338.51 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2022.229732 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ahmed Amin Ibrahim  ; Hanan Ali Taha; Rabab Afifi Mohammed; Shahenaz Hamdi El Genedi Khalil; Nilly Abd-Allah
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| Abstract | ||||
| Background: Although most patients with chronic hepatitis C are asymptomatic, an appreciable number will experience symptoms that are due to liver disease and /or extrahepatic manifestations of HCV infection. Recognition of these symptoms will lead to early diagnosis and treatment of hepatitis C. Objective: This study aimed to assess the prevalence of extrahepatic manifestations in patients with chronic hepatitis c infection in Beni-Suef Governorate. Patients and methods: 200 patients with CHC are studied, their ages ranged between 20-60 years. They are collected randomly from Beni-Suef University and general hospitals and outpatient clinics. Results: There is a wide range of prevalence of EHMS of HCV infection, 8% were asymptomatic and accidentally discovered to have HCV. 92% of the total number of patients have at least one EHM. The commonest extrahepatic manifestations are rheumatological 51%, hematological 26%, fatigue 20%, dermatological 19%, neurological 16%, DM11%, cryoglobulinemia 9% and less common chest, renal, lymphoproliferative disorders, cardiac, thyroid dysfunction. Conclusion: Extrahepatic manifestations appear earlier than hepatic manifestations of HCV patients. Age and liver fibrosis are considered major risk factors of EHMs. Health professionals should be aware of these HCV-associated complications and presentations. | ||||
| Keywords | ||||
| HCV; Autoimmune manifestations; Drugs; Hepatic manifestations | ||||
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