Utility of Carbothiohydrazides in Synthesis of some New Heterocyclic Compounds with Five- and Six-Membered Rings
Moustafa, A., Ahmed, D., Mohamed, M., El-Wassimy, M. (2022). Utility of Carbothiohydrazides in Synthesis of some New Heterocyclic Compounds with Five- and Six-Membered Rings. EKB Journal Management System, 7(1), 1-8. doi: 10.21608/sjsci.2022.233166
Amr H. Moustafa; Doaa H. Ahmed; Mamdouh F. A. Mohamed; M. T. El-Wassimy. "Utility of Carbothiohydrazides in Synthesis of some New Heterocyclic Compounds with Five- and Six-Membered Rings". EKB Journal Management System, 7, 1, 2022, 1-8. doi: 10.21608/sjsci.2022.233166
Moustafa, A., Ahmed, D., Mohamed, M., El-Wassimy, M. (2022). 'Utility of Carbothiohydrazides in Synthesis of some New Heterocyclic Compounds with Five- and Six-Membered Rings', EKB Journal Management System, 7(1), pp. 1-8. doi: 10.21608/sjsci.2022.233166
Moustafa, A., Ahmed, D., Mohamed, M., El-Wassimy, M. Utility of Carbothiohydrazides in Synthesis of some New Heterocyclic Compounds with Five- and Six-Membered Rings. EKB Journal Management System, 2022; 7(1): 1-8. doi: 10.21608/sjsci.2022.233166

Utility of Carbothiohydrazides in Synthesis of some New Heterocyclic Compounds with Five- and Six-Membered Rings

Sohag Journal of Sciences
Article 1, Volume 7, Issue 1, January 2022, Pages 1-8    PDF (691.85 K)
Document Type: Regular Articles
DOI: 10.21608/sjsci.2022.233166
Authors
Amr H. Moustafa* 1; Doaa H. Ahmed1; Mamdouh F. A. Mohamed2; M. T. El-Wassimy1
1Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt
2Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, Egypt
Abstract
Abstract: In this work we studied the reaction of carbohydrazides with some reagents having electrophilic centers such as
arylmethylenemalononitrile, aromatic aldehydes, bis(methylthio)methylenemalononitrile, dimethyl acetylene-dicarboxylate
and cyanoguanidine. The resulting products are five-membered heterocyclic rings such as thiadiazoles, thiazoles, triazoles;
and six-membered heterocyclic rings such as triazines.
Keywords
Carbothiohydrazide; Thiosemicarbazide; Thiocarbohydrazide; Triazole; Cyanoguanidine
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