Do CRP levels predict severity in COVID-19 hospitalized Egyptian patients?
Moneer, M., Fouad, S., Allam, M., Taha, S., Okba, A., Hosny, A., El-Moussely, L., Roman, S. (2022). Do CRP levels predict severity in COVID-19 hospitalized Egyptian patients?. EKB Journal Management System, 3(3), 534-543. doi: 10.21608/mid.2022.129490.1264
Mayada Moneer; Shaimaa H. Fouad; Mohamed Farouk Allam; Sara I. Taha; Ahmed Ashraf Okba; Amr Hosny; Lamiaa M. El-Moussely; Sylvia Wefky Roman. "Do CRP levels predict severity in COVID-19 hospitalized Egyptian patients?". EKB Journal Management System, 3, 3, 2022, 534-543. doi: 10.21608/mid.2022.129490.1264
Moneer, M., Fouad, S., Allam, M., Taha, S., Okba, A., Hosny, A., El-Moussely, L., Roman, S. (2022). 'Do CRP levels predict severity in COVID-19 hospitalized Egyptian patients?', EKB Journal Management System, 3(3), pp. 534-543. doi: 10.21608/mid.2022.129490.1264
Moneer, M., Fouad, S., Allam, M., Taha, S., Okba, A., Hosny, A., El-Moussely, L., Roman, S. Do CRP levels predict severity in COVID-19 hospitalized Egyptian patients?. EKB Journal Management System, 2022; 3(3): 534-543. doi: 10.21608/mid.2022.129490.1264

Do CRP levels predict severity in COVID-19 hospitalized Egyptian patients?

Microbes and Infectious Diseases
Article 5, Volume 3, Issue 3, August 2022, Pages 534-543    PDF (343.31 K)
Document Type: Original Article
DOI: 10.21608/mid.2022.129490.1264
Authors
Mayada Moneer1; Shaimaa H. Fouad2; Mohamed Farouk Allam3; Sara I. Taha* 4; Ahmed Ashraf Okba5; Amr Hosny6; Lamiaa M. El-Moussely7; Sylvia Wefky Roman1
1Department of Internal Medicine/ Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University.
2Department of Internal Medicine / Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University.
3Department of Family Medicine, Faculty of Medicine, Ain Shams University
4Department of Clinical Pathology, Faculty of Medicine, Ain Shams University.
5Department of Radiology, Faculty of Medicine, Ain Shams University.
6Department of Anesthesiology and Intensive care, Faculty of Medicine, Ain Shams University.
7Department of Medical Microbiology and Immunology, Faculty of Medicine, Ain Shams University.
Abstract
Background:  Coronavirus disease 2019 (COVID-19) is a rapidly spreading virus with a wide range of clinical manifestations. To manage treatment programs and promptly assess patient severity, prognostic factors must be identified early. Objectives: The purpose of this study was to investigate if there was a link between the severity of COVID-19 and the C-reactive protein (CRP) level on admission. Methods: On admission clinical and laboratory data from 323 patients with laboratory-confirmed COVID-19 were gathered from an Isolation Hospital records from April 10, 2020 to July 30, 2020. CRP was determined in all participants using an automated analyzer and a commercially available latex-enhanced immuno-turbidimetric assay. Results: The most prevalent presenting symptom was fever (39.3%), followed by cough (38.4%).  Coronavirus disease 2019 severity and ICU admission were both predicted by high CRP levels (p < /em><0.001).  C-reactive protein levels were also greater in those who had more chest discomfort, as indicated by CT chest abnormalities (p < /em><0.001). Conclusion: Serum CRP is a simple and effective prognosticator for early prediction of COVID-19 severity.
Keywords
COVID-19; CRP; Hospital admission; ICU; Severity
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