Investigation of COVID-19 By Theoretical Docking of Medicines With Two Proteins | ||
| Egyptian Journal of Chemistry | ||
| Volume 65, Issue 131, December 2022, Pages 247-253 PDF (584.9 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2022.117309.5292 | ||
| Authors | ||
| Ammar A. Ibrahim* 1; Mohammed F. Haddad2; Maher A. Ibrahim3; Ali W. Kasim4 | ||
| 1Department of Chemistry, College of Science, University of Mosul, Mosul, Iraq | ||
| 2Northern Technical University, IRAQ | ||
| 3Department of Biochemistry, College of Medicine, University of Mosul, IRAQ | ||
| 4Ministry of Health, IRAQ | ||
| Abstract | ||
| This study examined the docking of two inhibition for SARS-Cov-2 virus (or COVID-19) these proteins are (6wtt and 6xa4) with nine pharmaceutical compounds (Aminoglutethimide, 4-Aminosalicylic acid, Felbamate, Hydroflumethiazide, Modafinil, Nepafenac, Oxcarbazepine, and Trichlormethiazide) which are used in the general human's life. These pharmaceuticals having different active groups in the structure conformation like (-NH2) and (-OH). Docking was applied the investigate the interaction between these medicines with the proteins using Molecular Operating Environment software (MOE). | ||
| Keywords | ||
| COVID-19; Docking; Proteins; ligand-receptor interaction | ||
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