New Derivatives from 4-Amino Anti-Pyrine and Vanillin, Synthesis Characterization and Antibacterial Activity
Alabidi, H., Farhan, A., Al-labban, H., Aljanaby, A. (2023). New Derivatives from 4-Amino Anti-Pyrine and Vanillin, Synthesis Characterization and Antibacterial Activity. EKB Journal Management System, 66(1), 175-181. doi: 10.21608/ejchem.2022.135727.5977
Hawraa M Alabidi; Ali M Farhan; Hutham Mahmood Yousif Al-labban; Ahmed Abduljabbar Jaloob Aljanaby. "New Derivatives from 4-Amino Anti-Pyrine and Vanillin, Synthesis Characterization and Antibacterial Activity". EKB Journal Management System, 66, 1, 2023, 175-181. doi: 10.21608/ejchem.2022.135727.5977
Alabidi, H., Farhan, A., Al-labban, H., Aljanaby, A. (2023). 'New Derivatives from 4-Amino Anti-Pyrine and Vanillin, Synthesis Characterization and Antibacterial Activity', EKB Journal Management System, 66(1), pp. 175-181. doi: 10.21608/ejchem.2022.135727.5977
Alabidi, H., Farhan, A., Al-labban, H., Aljanaby, A. New Derivatives from 4-Amino Anti-Pyrine and Vanillin, Synthesis Characterization and Antibacterial Activity. EKB Journal Management System, 2023; 66(1): 175-181. doi: 10.21608/ejchem.2022.135727.5977

New Derivatives from 4-Amino Anti-Pyrine and Vanillin, Synthesis Characterization and Antibacterial Activity

Egyptian Journal of Chemistry
Volume 66, Issue 1, January 2023, Pages 175-181    PDF (785.19 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2022.135727.5977
Authors
Hawraa M Alabidi1; Ali M Farhan2; Hutham Mahmood Yousif Al-labban* 1; Ahmed Abduljabbar Jaloob Aljanaby3
1Department of Chemistry, Faculty of Science, University of Kufa, Iraq
2Ministry of Education, Al-Najaf, Iraq
3Department of Biology, Faculty of Science, University of Kufa, Iraq
Abstract
Schiff base, Azo-Schiff base, nickel (II), and copper (II) complexes have been prepared successfully from 4-amino antipyrine and vanillin and diagnosed by UV-visible, FT-IR, 1H-NMR, and 13C-NMR. The derivative compound Azo-Schiff with a 200 mg/ml concentration has good antibacterial activity with a diameter of inhibition zone 16.11 ± 0.1035 mm and 13.21 ± 0.4044 against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa), respectively. Therefore, this compound may be considered a raw material for manufacturing treatments against these bacterial infections.
Keywords
4-Amino antipyrine; Azo schiff base; Complexes; Biological activity; S. aureus; P. aeruginosa
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