New Derivatives from 4-Amino Anti-Pyrine and Vanillin, Synthesis Characterization and Antibacterial Activity | ||
| Egyptian Journal of Chemistry | ||
| Volume 66, Issue 1, January 2023, Pages 175-181 PDF (785.19 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2022.135727.5977 | ||
| Authors | ||
| Hawraa M Alabidi1; Ali M Farhan2; Hutham Mahmood Yousif Al-labban* 1; Ahmed Abduljabbar Jaloob Aljanaby3 | ||
| 1Department of Chemistry, Faculty of Science, University of Kufa, Iraq | ||
| 2Ministry of Education, Al-Najaf, Iraq | ||
| 3Department of Biology, Faculty of Science, University of Kufa, Iraq | ||
| Abstract | ||
| Schiff base, Azo-Schiff base, nickel (II), and copper (II) complexes have been prepared successfully from 4-amino antipyrine and vanillin and diagnosed by UV-visible, FT-IR, 1H-NMR, and 13C-NMR. The derivative compound Azo-Schiff with a 200 mg/ml concentration has good antibacterial activity with a diameter of inhibition zone 16.11 ± 0.1035 mm and 13.21 ± 0.4044 against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa), respectively. Therefore, this compound may be considered a raw material for manufacturing treatments against these bacterial infections. | ||
| Keywords | ||
| 4-Amino antipyrine; Azo schiff base; Complexes; Biological activity; S. aureus; P. aeruginosa | ||
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