Contested role of procalcitonin and C-reactive protein in the diagnosis of fascioliasis | ||||
| Parasitologists United Journal | ||||
| Article 13, Volume 15, Issue 1, April 2022, Page 117-120 PDF (315.35 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/puj.2022.117557.1148 | ||||
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| Authors | ||||
| Fatih Cakir* 1; Alican Bilden2; Nida Ozcan3; Mutalip Cicek4 | ||||
| 1Departments of Medical Microbiology , Faculties of Medicine, Dicle University, Diyarbakır | ||||
| 2Departments of Parasitology , Faculties of Medicine, Ahi Evran University, Kırşehir , Turkey | ||||
| 3Departments of Medical Microbiology Faculties of Medicine, Dicle University, Diyarbakır | ||||
| 4Departments of Medical Parasitology , Faculties of Medicine, Ahi Evran University, Turkey | ||||
| Abstract | ||||
| Background: Procalcitonin (PCT) and C-reactive protein (CRP) are acute phase reactants indicating inflammation, particularly in bacterial infections. High PCT or CRP levels were proposed in malaria, invasive amoebiasis, babesiosis and schistosomiasis. Since liver is the sole habitat, it was hypothesized that PCT and CRP may have a role in the diagnosis of fascioliasis. Objective: The study aimed to investigate whether PCT and CRP have a role in the diagnosis of fascioliasis. Subjects and Methods: Fifty fascioliasis patients and 50 healthy blood donors in the same age range, as the control group, were included in the study. Fascioliasis was diagnosed by anti-Fasciola IgG ELISA, in addition, direct stool examinations (fresh smear and after sedimentation) were performed in both groups. Serum PCT and CRP levels were determined by I-chroma kits on I- CHROMA™ II device, and NFL BN-II immunonephelometry system, respectively. Results: There was no statistically significant difference of PCT and CRP values between the fascioliasis patient group and the control group (P> 0.05). Conclusion: It was concluded that PCT and CRP were not relevant parameters for diagnosis of fascioliasis | ||||
| Keywords | ||||
| diagnosis; fascioliasis; procalcitonin; C-reactive protein | ||||
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