Protective effect of Globe Artichoke (Cynara Scolymus L.) on Growing Male Rats Fed on High Fat and Fructose diet | ||
| مجلة دراسات وبحوث التربية النوعية | ||
| Volume 3, Issue 1 - Serial Number 5, January 2017, Pages 345-363 PDF (487.54 K) | ||
| Document Type: المقالة الأصلية | ||
| DOI: 10.21608/jsezu.2017.238356 | ||
| Author | ||
| O.I. El-Nahas | ||
| Home Economics Department, Faculty of Specific Education, Mansoura University, Mansoura Egypt | ||
| Abstract | ||
| The present study was carried out to investigate the effect of globe artichoke on high fat and fructose (HF/HFr) diet on the onset of the characteristics of the the levels of growing male. Also the possible protective effects of artichoke (AK) against (HF/HFr) diet induced-metabolic disturbances. Thirty sex male albino rats were randomly assigned into 4 groups and were fed for 6 weeks the following diets group 1 basal diet, negative control (C) group 2 basal diet containing 20 g AK/kg diet (C+AK), group 3 high fat diet (15% beef tallow + 5% corn oil) combined with fructose (13% W/V) in drinking water (HF/HFr), group 4 HF/HFr diet containing 20 g AK/kg diet (HF/HFr+AK). HF/HFr diet induced elevated levels of blood glucose, serum TG, TC, LDL-C, liver, renal function and (NO) with a decrease in (HDL-C) and total antioxidant capacity compared to control. These effects were more pronounced in HF/HFr diet fed on. Globe artichoke reinstated most of the altered measured parameters. So, HF/HFr diet developed characteristics of metabolic syndrome in growing male rats. Artichoke were protected against some metabolic disturbances of HF/HFr diet. The inclusion of artichoke consumption has a beneficial effect in control and management of diabetes and diabetes associated complications with no risk of hypoglycemic effect. | ||
| Keywords | ||
| Cynara scolymus L; Metabolic syndrome; Phenolic compounds; HF/ HFr diet | ||
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