Synthesis of Some Novel Pyridine, Sulfonamide, Coumarin and Thiophene Derivatives | ||
| Egyptian Journal of Chemistry | ||
| Volume 66, Issue 2, February 2023, Pages 349-355 PDF (611.48 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2022.135732.5979 | ||
| Authors | ||
| Ammar H. Al-Sabawi* 1; Shahla A. Younis1; Rana A. Saeed2 | ||
| 1Department of Chemistry, College of Science, University of Mosul, Mosul, IRAQ | ||
| 2Department of Pharmaceutical, Mosul Technical Institute, Northern Technical University, Mosul, IRAQ. | ||
| Abstract | ||
| A series of novel pyridine, sulfonamide, coumarin, thiophene, α,β-unsaturated carbonyl compounds, and pyrazole derivatives were synthesized from hydrazide-hydrazone derivatives with different reagents (substituted benzaldehydes, hydrazine hydrate, malononitrile, 2-hydroxy-1-naphthaldehyde, tetralone, cyclopentanone, and ethyl cyanoacetate). Hydrazide-hydrazone derivatives were prepared by reactions 2-cyanoacetohydrazide with 2-acetylpyridine or 4-acetyl-N-(p-tolyl)benzenesulfonamide. On the basis of their spectral information, the structures of the newly synthesized chemical derivatives were determined. | ||
| Keywords | ||
| 2-cyanoaceto hydrazide; 4-acetyl-N-(p-tolyl)benzenesulfonamide; pyridine; sulfonamide; coumarin; thiophene; and pyrazoles derivatives | ||
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