Efficacy of three hormonal treatments for cystic ovarian disease and subsequent reproductive performance in dairy cows | ||||
| Damanhour Journal of Veterinary Sciences | ||||
| Article 2, Volume 8, Issue 1, May 2022, Page 6-10 PDF (386.77 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/djvs.2021.99394.1053 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Mohamed A. Elbehiry  1; Mostafa Mahboob1; Mohamed Marey1; Sayed Hattab2; Rezk Ghallab3; Ragab Dohreig4
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| 1Department of Theriogenology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt | ||||
| 2Department of Theriogenology, Faculty of Veterinary Medicine, Alexandria University, Egypt | ||||
| 3Department of Theriogenology, Faculty of Veterinary Medicine Matrouh University, Egypt | ||||
| 4Animal Reproduction Research Institute (ARRI), Agriculture Research Center (ARC), Egypt | ||||
| Abstract | ||||
| Cystic ovarian disease (COD) is a common ovarian disorder that causes major reproductive failure in dairy cows leading to significant economic losses in the dairy industry. This study aimed to evaluate the efficacy and the response of cows with ovarian cysts to three different treatments regardless of the cyst type. At 50 days postpartum, were considered to have an ovarian cyst when possessing a follicle with a diameter ≥ 17 mm in the absence of a corpus luteum in two ultrasonographic examinations performed at 7 days intervals. In the second examination considered (Day 0), 51 cystic Holstein cows were assigned randomly into one of 3 treatment groups.; GnRH group (n=12) treated with 100 μg gonadorelin as a single dose, GP group (n=12) received (100 μg gonadorelin on day 0 followed by 500 μg of cloprostenol sodium on day 7, CIDR group (n=12) treated with intravaginal progesterone-releasing insert CIDR on the day 0: and 100 μg gonadorelin then an injection of 500 µg cloprostenol sodium IM on day 7. The CIDR was removed on day 8, and a second GnRH injection was given on day 9. From day 9, animals were observed for estrus and inseminated with proven frozen-thawed semen. Control Group (n=15) represents cows that did not receive any treatment. Pregnancy was confirmed by ultrasound on day 28 post-insemination. Results showed that the GP group achieved the highest estrus induction rate (EIR). Thus, 44.4% of treated cows come in estrus less than 10 days and 100 % by day 20. While GnRH group showed EIR with 25% in less than 10 days and 62.5 % at the day 20. The CIDR group showed EIR (0%) in less than 10 days and 100 % at the day 20. Total conception rate (3 cycles after treatment) GP recorded (88.9%) GnRH group (87.5%) and CIDR (85.7%), while pregnancy rates (PR) was highest (66.7%) in GP protocol compared to GnRH (58.3%), and CIDR (49.9%). In conclusion, our results showed that the (GP group) had the best reproductive performance (earliest and highest estrus induction rate and highest pregnancy rate after treatment regardless of the type of the cyst. | ||||
| Keywords | ||||
| Cystic ovarian disease; GnRH; CIDR; Estrus | ||||
| References | ||||
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Ambrose, D. J., Schmitt, E. J., Lopes, F. L., Mattos, R. C., & Thatcher, W. W. (2004). Ovarian and endocrine responses associated with the treatment of cystic ovarian follicles in dairy cows with gonadotropin releasing hormone and prostaglandin F2α, with or without exogenous progesterone. The Canadian Veterinary Journal, 45(11), 931. Amer, H., & Badr, A. (2008). Hormonal profiles associated with treatment of cystic ovaries with GnRH and PGF2α with and without CIDR in dairy cows. Journal of Applied Biological Sciences, 2(1), 51-56. Bartlett, P. C., Ngategize, P. K., Kaneene, J. B., Kirk, J. H., Anderson, S. M., & Mather, E. C. (1986). Cystic follicular disease in Michigan Holstein-Friesian cattle: Incidence, descriptive epidemiology and economic impact. Preventive Veterinary Medicine, 4(1), 15-33. Bartolome, J. A., Archbald, L., Morresey, P., Hernandez, J., Tran, T., Kelbert, D., . . . Thatcher, W. (2000). Comparison of synchronization of ovulation and induction of estrus as therapeutic strategies for bovine ovarian cysts in the dairy cow. Theriogenology, 53(3), 815-825. Bierschwal, C. (1966). A clinical study of cystic conditions of the bovine ovary. J Am Vet Med Assoc, 149, 1591-1595. Bierschwal, C., Garverick, H., Martin, C., Youngquist, R., Cantley, T., & Brown, M. (1975). Clinical response of dairy cows with ovarian cysts to GnRH. Journal of animal science, 41(6), 1660-1665. BorŞ, S. I., & BorŞ, A. (2020). Ovarian cysts, an anovulatory condition in dairy cattle. J Vet Med Sci, 82(10), 1515-1522. doi:10.1292/jvms.20-0381 Borsberry, S., & Dobson, H. (1989). Periparturient diseases and their effect on reproductive performance in five dairy herds. The Veterinary Record, 124(9), 217-219. Brann, D. W., Chorich, L. P., & Mahesh, V. B. (1993). Effect of progesterone on galanin mRNA levels in the hypothalamus and the pituitary: correlation with the gonadotropin surge. Neuroendocrinology, 58(5), 531-538. Butler, W. R. (2003). Energy balance relationships with follicular development, ovulation and fertility in postpartum dairy cows. Livestock production science, 83(2-3), 211-218. Calder, M. D., Salfen, B. E., Bao, B., Youngquist, R. S., & Garverick, H. A. (1999). Administration of progesterone to cows with ovarian follicular cysts results in a reduction in mean LH and LH pulse frequency and initiates ovulatory follicular growth. Journal of animal science, 77(11), 3037-3042. Carroll, D., Pierson, R., Hauser, E., Grummer, R., & Combs, D. (1990). Variability of ovarian structures and plasma progesterone profiles in dairy cows with ovarian cysts. Theriogenology, 34(2), 349-370. Colazo, M. G., & Mapletoft, R. J. (2014). A review of current timed-AI (TAI) programs for beef and dairy cattle. The Canadian Veterinary Journal, 55(8), 772. Dinsmore, R. P., White, M. E., & English, P. B. (1990). An evaluation of simultaneous GnRH and cloprostenol treatment of dairy cattle with cystic ovaries. The Canadian Veterinary Journal, 31(4), 280. Douthwaite, R., & Dobson, H. (2000). Comparison of different methods of diagnosis of cystic ovarian disease in cattle and an assessment of its treatment with a progesterone‐releasing intravaginai device. Veterinary Record, 147(13), 355-359. Garverick, H. A. (1997). Ovarian follicular cysts in dairy cows. J Dairy Sci, 80(5), 995-1004. doi:10.3168/jds.S0022-0302(97)76025-9 Ginther, O., Knopf, L., & Kastelic, J. (1989). Temporal associations among ovarian events in cattle during oestrous cycles with two and three follicular waves. Reproduction, 87(1), 223-230. Hanzen, C. (1984). The role of prostaglandins in human and animal reproductive physiology [cow, ewe, goat]. Journal de Gynecologie Obstetrique et Biologie de la Reproduction (France). Hatler, T., Hayes, S., Anderson, L., & Silvia, W. (2006). Effect of a single injection of progesterone on ovarian follicular cysts in lactating dairy cows. The Veterinary Journal, 172(2), 329-333. Kahn, C., Line, S., & Aiello, S. (2010). The Merck Veterinary Manual. 10th edn, Whitehouse Station, NJ: Merck and Co. Chrysomya bezziana, 822-823. Kesler, D., & Garverick, H. (1982). Ovarian cysts in dairy cattle: a review. Journal of animal science, 55(5), 1147-1159. Kim, I.-H., Suh, G.-H., Kim, U.-H., & Kang, H.-G. (2006). A CIDR-based timed AI protocol can be effectively used for dairy cows with follicular cysts. Animal Reproduction Science, 95(3-4), 206-213. Kinder, J., Kojima, F., Bergfeld, E., Wehrman, M., & Fike, K. (1996). Progestin and estrogen regulation of pulsatile LH release and development of persistent ovarian follicles in cattle. Journal of animal science, 74(6), 1424-1440. Lee, L., Ferguson, J., & Galligan, D. (1988). The use of survival analysis to quantitate days open: advantages and applications. Acta veterinaria Scandinavica. Supplementum, 84, 433-435. Lopez-Gatius, F., & Lopez-Bejar, M. (2002). Reproductive performance of dairy cows with ovarian cysts after different GnRH and cloprostenol treatments. Theriogenology, 58(7), 1337-1348. López-Gatius, F., Santolaria, P., Yániz, J., Rutlant, J., & López-Béjar, M. (2001). Persistent ovarian follicles in dairy cows: a therapeutic approach. Theriogenology, 56(4), 649-659. Mollo, A., Stradaioli, G., Gloria, A., & Cairoli, F. (2012). Efficacy of different ovarian cysts treatments (GnRH, hCG and PRID) in dairy cows. Naor, Z., Jabbour, H. N., Naidich, M., Pawson, A. J., Morgan, K., Battersby, S., . . . Millar, R. P. (2007). Reciprocal cross talk between gonadotropin-releasing hormone (GnRH) and prostaglandin receptors regulates GnRH receptor expression and differential gonadotropin secretion. Molecular Endocrinology, 21(2), 524-537. NRC. (2001). Nutrient requirements of dairy cattle: 2001: National Academies Press. Peter, A. (2004). An update on cystic ovarian degeneration in cattle. Reproduction in domestic animals, 39(1), 1-7. Probo, M., Comin, A., Mollo, A., Cairoli, F., Stradaioli, G., & Veronesi, M. C. (2011). Reproductive performance of dairy cows with luteal or follicular ovarian cysts after treatment with buserelin. Animal Reproduction Science, 127(3-4), 135-139. Purohit, G. N. (2008). Recent developments in the diagnosis and therapy of repeat breeding cows and buffaloes. CAB Reviews: Perspectives in Agriculture Veterinary Science Nutrition and Natural Resource, 3(62), 1-34. Randel, R., Lammoglia, M., Lewis, A., Neuendorff, D., & Guthrie, M. (1996). Exogenous PGF2α enhanced GnRH-induced LH release in postpartum cows. Theriogenology, 45(3), 643-654. Rauch, A., Krueger, L., Miyamoto, A., & Bollwein, H. (2008). Colour Doppler sonography of cystic ovarian follicles in cows. Journal of Reproduction and Development, 0809090095-0809090095. Saad, A. Y. (2013). Some Studies on Cystic Ovarian Disease in Dairy Cattle. (Ms Thesis Ms Thesis ), Zagazig University. Silvia, W., Hatler, T., Nugent, A., & Da Fonseca, L. L. (2002). Ovarian follicular cysts in dairy cows: an abnormality in folliculogenesis. Domestic animal endocrinology, 23(1-2), 167-177. Stevenson, J. (2012). Eleven truths about ovarian cysts. Hoard's Dairyman, 157(1), 21. Taktaz, T., Kafi, M., Mokhtari, A., & Heidari, M. (2015). Reproductive responses of dairy cows with ovarian cysts to simultaneous human chorionic gonadotropin or gonadotropin-releasing hormone and cloprostenol compared to gonadotropin-releasing hormone alone treatment. Veterinary world, 8(5), 640. Waheeb, R. S., & Hatab, S. A. (2017). Efficacy of Administration of Supplemental and Hormonal Therapies for Treatment of Postpartum True Anestrous Dairy Cows. Alexandria Journal for Veterinary Sciences, 52(1). Woolums, A. R., & Peter, A. T. (1994). Cystic ovarian condition in cattle. 1. Folliculogenesis and ovulation. Compendium on Continuing Education for the Practicing Veterinarian, 16(7), 935-&. Youngquist, R., & Threlfall, W. (2007). Ovarian follicular cysts. Current therapy in large animal theriogenology. St. Louis, MO: Saunders Elsevier, 379-383. | ||||
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