Role of High Mobility Group Box1 in Pathogenesis of Hepatitis C Virus induced Hepatocellular Carcinoma
Samra, N., El-Etreby, S., Mahdy, R., El-Kazzaz, S., El-Nashar, N. (2020). Role of High Mobility Group Box1 in Pathogenesis of Hepatitis C Virus induced Hepatocellular Carcinoma. EKB Journal Management System, 29(4), 135-141. doi: 10.51429/EJMM29417
Nouran E. Samra; Shahira El-Etreby; Rasha H. El- Mahdy; Samah S. El-Kazzaz; Nariman M. El-Nashar. "Role of High Mobility Group Box1 in Pathogenesis of Hepatitis C Virus induced Hepatocellular Carcinoma". EKB Journal Management System, 29, 4, 2020, 135-141. doi: 10.51429/EJMM29417
Samra, N., El-Etreby, S., Mahdy, R., El-Kazzaz, S., El-Nashar, N. (2020). 'Role of High Mobility Group Box1 in Pathogenesis of Hepatitis C Virus induced Hepatocellular Carcinoma', EKB Journal Management System, 29(4), pp. 135-141. doi: 10.51429/EJMM29417
Samra, N., El-Etreby, S., Mahdy, R., El-Kazzaz, S., El-Nashar, N. Role of High Mobility Group Box1 in Pathogenesis of Hepatitis C Virus induced Hepatocellular Carcinoma. EKB Journal Management System, 2020; 29(4): 135-141. doi: 10.51429/EJMM29417

Role of High Mobility Group Box1 in Pathogenesis of Hepatitis C Virus induced Hepatocellular Carcinoma

Egyptian Journal of Medical Microbiology
Volume 29, Issue 4, October 2020, Pages 135-141    PDF (562.53 K)
Document Type: Review articles
DOI: 10.51429/EJMM29417
Authors
Nouran E. Samra* 1; Shahira El-Etreby2; Rasha H. El- Mahdy1; Samah S. El-Kazzaz1; Nariman M. El-Nashar1
1Department of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University
2Hepatology & Gastroenterology unit, Faculty of Medicine, Mansoura University
Abstract
Hepatocellular carcinoma "HCC" is a leading cause of cancer mortality worldwide. High-mobility group box 1 "HMGB1" is a nuclear DNA-binding protein which involved in DNA stability, programmed cell death, immune response and inflammatory responses in HCV and HCC. Its over expression was revealed in HCC and different types of human cancers.
Keywords
HMGB1; HCV; HCC; Cancer; HMGB1 receptors
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