Effect of Acute Zinc Administration on Essential Metal Levels in Liver, Kidney, Lung and Heart of the Male Egyptian Toad Bufo Regularis | ||||
| Journal of High Institute of Public Health | ||||
| Article 5, Volume 30, Issue 3, July 2000, Page 473-480 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jhiph.2000.252702 | ||||
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| Authors | ||||
| F I. Moussa1; W Abou Samara2; A A. El-Masry1 | ||||
| 1Zoology Department, Faculty of Science, Alexandria University, Egypt | ||||
| 2Biology Department, Faculty of Education, Alexandria University, Egypt | ||||
| Abstract | ||||
| To compare the organ injuries by Zn2+ a concentration of 48 mg Zn/kg body weight which represents to LD50 was administered intramuscularlly to the male Egyptian toad Buflo regulasis. Median lethal concentration values [LD50] were 68, 62, 54 & 48 mg Zn/kg body weight for 24, 48, 72 and 96 hr respectively. The changes in the concentration of 6 essential metals [Zn, Fe, Cu, Ca, Mg & Mn] were determind in liver, kidney, heart and lung of he male Egyptian toad Bufo regularis. Marked alterations in hepatic metal levels [increases of Zn, Cu & Ca accompanied by a decrease in Fe content were observed. Renal Zn and Cu Concentrations were increased while renal magnesium was decreased. A significant depletion in Mg content was observed in the heart of the treated toad, while Mn content was increased in the lung of the treated toad. | ||||
| Keywords | ||||
| Toad; Zinc; Calcium; Copper | ||||
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