3-Aryl/hetaryl-2-cyanoacryloyl chlorides: Synthesis and Reactions with Binucleophiles Targeting Heterocycles | ||
| Egyptian Journal of Chemistry | ||
| Article 52, Volume 65, Issue 11, November 2022, Pages 565-572 PDF (567.93 K) | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2022.152901.6621 | ||
| Authors | ||
| Eman A. E. El-Helw1; Ahmed Kamel El-Ziaty* 2; sayed Karam Ramadan3 | ||
| 1Chemistry Department, Faculty of Science, Ain Shams University, Abassia, Cairo, Egypt | ||
| 2Ain shams University | ||
| 3chem.dept.asu | ||
| Abstract | ||
| In this review, we reported the synthetic method used to construct thirteen derivatives of 3-aryl/heteryl-2-cyanoacryloyl chloride followed by a focused survey on their spectral data and the synthetic importance of this scaffold for building a wide variety of heterocyclic skeletons using three different types of bidentate nucleophiles. | ||
| Keywords | ||
| Acryloyl chlorides; Activated nitrile; Bidentate Nucleophiles; Fused Heterocycles | ||
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