Chemical and biological studies of Thyme based on different solvents extraction | ||
| Egyptian Journal of Chemistry | ||
| Article 26, Volume 66, Issue 6, June 2023, Pages 247-253 PDF (658.6 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2022.155704.6721 | ||
| Authors | ||
| Yasser Selim* ; Hany Helmy; Mennat-allah Hamed; Nehal Abdel-latif | ||
| Faculty of Specific Education, Zagazig University, Zagazig, 44519, Egypt. | ||
| Abstract | ||
| Thyme was employed in this work to analyze the overall composition using its methanolic and ethanolic extracts. protocatechuic acid, p-hydroxybenzoic acid, rosmarinic acid, cateachin, caffeic acid, apigenin, kaempferol, ferulic acid, and rutin were the most potant bioactive compounds of thyme extracts. These substances have antimicrobial properties against G+ bacteria and G- bacteria. It is also necessary to test thyme and its extracts for their efficacy in vivo in order to confirm the findings of the current investigation. With respect to G+ bacteria (Bacillus cereus and Staphylococcus aureus), G- bacteria (Escherichia coli and Pseudomonas aeruginosa), and fungi (Candida albicans), the ethanolic and methanolic extracts have anti-microbial activity (Ampicillin as antibacterial agent and Amphotericin B as antifungal agent). | ||
| Keywords | ||
| Thymus; polyphenolic; antimicrobial activity; HPLC analysis | ||
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