Maternal Environmental Tobacco Smoke during Pregnancy and Risk of Congenital Heart | ||
| The Medical Journal of Cairo University | ||
| Volume 90, Issue 9, September 2022, Pages 1715-1720 PDF (57.62 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjcu.2022.272093 | ||
| Authors | ||
| EMAN M. EL-SAYED, M.D.; MONA M. EL-GANZORY, M.D.; GHADA I. EL-MOKADEM, M.Sc. | ||
| The Department of Pediatrics, Faculty of Medicine, Ain Shams University | ||
| Abstract | ||
| Abstract Background: To examine the correlation between maternal environmental tobacco smoking during pregnancy as well as the risk of congenital heart defects (CHDs) incidence in offspring. Aim of Study: To examine the correlation between maternal environmental tobacco smoking throughout pregnancy and the CHD incidence risk in offspring. Patients and Methods: This is a case-control study that was conducted on two groups of patients presented to the Pediatric Cardiology Unit, Ain Shams University Hospitals, including group 1: 120 mother of live born infant diagnosed with congenital heart disease confirmed by echocardiography done by a specialized echocardiologist, And group 2: 120 mother of infant with normal heart, using questionnaire. Work start at May 2020 and end in May 2021. Results: There was a statistically significant increase in the incidence ofCHDs among children whose mothers have been exposed to smoking during pregnancy than those with no history of exposure (p-value=0.003). There was also a substantially elevated risk of CHD with respect to time of exposure during pregnancy (p-value=0.001). Additionally, There was a statistically significant increase in CHDs incidence among children whose mothers had a history of the first trimester and preconception smoking exposure. ETS (ENVI-RONMENTAL TOBACCO SMOKE) >15 minper day (p-value=0.007 being more ingroup of mothers with children with CHDs. Conclusions: Maternal exposure to smoking substantially impacts the increased incidence of CHDs in general. This study observed that maternal ETS >15 minutes per day (passive smoking) is associated with increased CHDs. | ||
| Keywords | ||
| Environmental tobacco smoking; CHD; Preg-nancy | ||
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