Impact of Ablative Low Dose Radio-Active Iodine after Thyroidectomy in Low–Risk Differentiated Thyroid Cancer | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 147, Volume 89, Issue 2, October 2022, Pages 7082-7090 PDF (742.1 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2022.273046 | ||
| Authors | ||
| Lamiaa Ahmed Elrefai* ; Magda Elsayed Hassan Allam; Mohamed Saad El-deen El-zahi; Fatma Mohamed Farouk Akl | ||
| Clinical Oncology& Nuclear Medicine Department, Faculty Of Medicine, Mansoura University. | ||
| Abstract | ||
| Background:Thyroid cancer (TC) is the most frequent endocrine cancer, comprising for 3-4% of all tumors. Objective: The aim of the current study was to assess the efficacy, safety, and disease-free survival of low-dose RAI (iodine-131) in patients with low-risk differentiated thyroid cancer (DTC) who had low-dose RAI for thyroid residual ablation after full or near-total thyroidectomy. Patients and methods: Between January 2013 and July 2019, 35 patients with low-risk well-differentiated thyroid cancer were investigated by the Clinical Oncology and Nuclear Department at Mansoura University Hospitals. Results: The majority of our patients (94.3%) were females. A total of 34 (97.1%) patients had papillary thyroid cancer and 1 (2.8 %) patient had follicular thyroid carcinoma. All patients were Stage I; 13 (37.1%) patients were T1, and 22 (62.9%) patients were T2 thyroid carcinoma. All patients had pathologically negative lymph nodes and 8 (22.8%) patients had complete thyroidectomy with block neck dissection (BND), whereas the remaining 27 (77.1%) patients had total thyroidectomy without BND. Conclusion: Low-dose radioactive iodine ablation following surgery is an effective approach for treating low-risk DTC, because it decreases the side effects while preserving a good quality of life. | ||
| Keywords | ||
| Ablative low dose radio-active iodine; Thyroidectomy; Papillary thyroid cancer; Follicular thyroid carcinoma; Thyroid cancer; Case series; Mansoura University | ||
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