Uterine and ovarian blood flow in mares treated with silver oxide nanoparticles | ||
| Veterinary Medical Journal (Giza) | ||
| Article 7, Volume 68, Issue 1, 2022, Pages 95-103 PDF (419.52 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/vmjg.2022.183055.1017 | ||
| Authors | ||
| Ibrahim Emad Ibrahim hamama* 1; refaat sobhy ahmed ragab2; el shimaa ahmed abdelnaby3; amal mahmoud aboelmaaty4 | ||
| 1Theriogenology, veterinary medicine, cairo university , giza , egypt | ||
| 2theriogenology ,veterinary medicine cairo university | ||
| 3theriogenology | ||
| 4Animal Reproduction and AI Dept., Veterinary Division, National Research Centre, Dokki, Giza, Egypt. | ||
| Abstract | ||
| This study aimed to investigate the influence of treatment with silver oxide nanoparticles intrauterine infusion on ovarian and uterine blood flow, cortisol, estradiol (E2) and interlukine-10 (IL-10). Mares (N=8), diagnosed positive to endometritis, were examined by Doppler ultrasonography. Blood samples were collected prior to each ultrasound exam.. Blood sera were used to assay cortisol, E2, and IL-10. The uterine and ovarian arteries’ time average mean velocity (TAMV) and blood flow volume(BFV) were determined. Mares were infused intrauterine with 50 mg/kg body weight of silver oxide nanoparticles on Day 7(from ovulation ) and another dose on Day 14 from ovulation . On day 21 from ovulation , there were significant decreases in BFV and TAMV values of the uterine (P< 0.001; P< 0.05, respectively) and ovarian arteries (P< 0.0001). A non-significant change in the cortisol and IL-10 was noticed throughout the treatment. In conclusion, silver oxide nanoparticles modulated uterine and ovarian blood flow in endometritis suffered mares on day 21 post-treatment. | ||
| Keywords | ||
| Endometritis; Ovarian hemodynamics; Mare; Nanoparticles; Interleukine 10 | ||
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