Prevalence of Congenital Heart Disease in Pediatric Patients with Down Syndrome in Fayoum Governorate
Amin, S., Mahmoud, H., Ibrahem, A., El-Awady, H. (2023). Prevalence of Congenital Heart Disease in Pediatric Patients with Down Syndrome in Fayoum Governorate. EKB Journal Management System, 11(2), 1-9. doi: 10.21608/fumj.2023.281381
Sayed Ali Amin; hanaa H. Mahmoud; Amany Y. Ibrahem; Heba A. El-Awady. "Prevalence of Congenital Heart Disease in Pediatric Patients with Down Syndrome in Fayoum Governorate". EKB Journal Management System, 11, 2, 2023, 1-9. doi: 10.21608/fumj.2023.281381
Amin, S., Mahmoud, H., Ibrahem, A., El-Awady, H. (2023). 'Prevalence of Congenital Heart Disease in Pediatric Patients with Down Syndrome in Fayoum Governorate', EKB Journal Management System, 11(2), pp. 1-9. doi: 10.21608/fumj.2023.281381
Amin, S., Mahmoud, H., Ibrahem, A., El-Awady, H. Prevalence of Congenital Heart Disease in Pediatric Patients with Down Syndrome in Fayoum Governorate. EKB Journal Management System, 2023; 11(2): 1-9. doi: 10.21608/fumj.2023.281381

Prevalence of Congenital Heart Disease in Pediatric Patients with Down Syndrome in Fayoum Governorate

Fayoum University Medical Journal
Volume 11, Issue 2, January 2023, Page 1-9  XML PDF (326.4 K)
Document Type: Full Length research Papers
DOI: 10.21608/fumj.2023.281381
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Authors
Sayed Ali Amin1; hanaa H. Mahmoud2; Amany Y. Ibrahem email 3; Heba A. El-Awady4
1Department of Pediatrics,Faculty of Medicine ,Fayoum University,Fayoum ,Egypt.
2Department of Pediatrics Fayoum university
3Department of Pediatrics,Faculty of Medicine ,Fayoum University,Fayoum , Egypt.
4Departemt of Pediatrics Fayoum university
Abstract
Introduction: Congenital heart disease (CHD) is the leading cause of mortality and morbidity during the first two years of the Down Syndrome (DS) patient's life. Studies showed that 40-63.5% of DS patients had CHD. The defects can involve the heart walls, valves, veins, and arteries. They might develop congestive heart failure, pulmonary vascular disease, pneumonia, or failure to thrive.
Aim of the study: The current study aimed to define the prevalence and patterns of congenital heart disease (CHD) among children with Down syndrome (DS) in Fayoum Governorate.
Subjects and Methods: The study recruited 150 pediatric DS patients from the cardiology and genetic clinics of Fayoum University Hospital, outpatient clinics of Fayoum General Hospital, and Fayoum Insurance Hospital. The current cross-sectional study was conducted for one year and nine months, January 2018 to September 2019.
Results: Echocardiographic examination of cases revealed that (54.7%) had CHD. Atrial septal defect (ASD) was the most frequent lesion (67.1%), followed by ventricular septal defect (VSD) (32.9%), patent ductus arteriosus (PDA) (18.3%), and atrioventricular septal defect (AVSD) in (13.4%) of cases.
Conclusion: There was a high incidence of CHD among pediatric DS patients. Acyanotic lesions were the most common ASD and VSD. Investigations included the 2D mode with color Doppler in Echocardiographic examination is considered the gold standard for diagnosis of CHD.
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