Does the price matter? potency comparative study for different Ceftriaxone generics in the Egyptian market
abdelaziz, M., Mohamed, N., ElKhatib, A., Mahmoud, Y., Hussein, M., Hassan, E., Saad, A., El-dammasy, D., Azmy, S., Elsayed, A., Elsayed, A., Abdel Aal, S., Abdelhamid, T., Mohamed, K., Ishak, F., Elsayed, A., Elsaied, Z., Ali, A., Ghrseldin, Y., Amer, A., Mahrous, M., Ibrahim, H., Hamed, H., Mostafa, M., Gamel, N., Khalil, N., Ibrahim, S., Ibrahim, N., Abdelmotalb, H., Mina, M., Hosni, A., Khalifa, H., Shaaban, H., Ibrahim, A., Elshahedy, M., Abdelkader, M., ElBadrawy, F., Ghareeb, N., Nagy, T., Mohamed, W., Abdelrahman, I., El-khamissy, T. (2023). Does the price matter? potency comparative study for different Ceftriaxone generics in the Egyptian market. EKB Journal Management System, 2(1), 210-218. doi: 10.21608/erurj.2023.188589.1007
Mohamed Taha abdelaziz; Nagwa Osama Mohamed; Ahmed Mohamed ElKhatib; Yehia Abdelmoniem Mahmoud; Marah Moustafa Hussein; Esraa Korayem Hassan; Amira Gamal Saad; Dalia Ali El-dammasy; Sara Wafdy Azmy; Amira Mohamed Elsayed; Ahmed Adel Elsayed; Sarah Hussein Abdel Aal; Tasnim Mohammed Abdelhamid; Kholoud Farag Mohamed; Fady Namr Ishak; Amira Adel Elsayed; Ziad Yasser Elsaied; Aya Mohamed Ali; Yara Hany Ghrseldin; Ahmed Sheref Amer; Mark Asaad Mahrous; Hager Abdelkader Ibrahim; Habiba Hany Hamed; Mariam Mohammad Mostafa; Norhan Sobhy Gamel; Noura Elsayed Khalil; Shahd Hany Ibrahim; Nada Medhat Ibrahim; Hanan Hatem Abdelmotalb; Maria Mounir Mina; Abdallah Ahmed Hosni; Hanaa Mahmoud Khalifa; Hadir Shaaban; Ahmed Mounir Ibrahim; Mohamed Ashraf Elshahedy; Mohamed Ahmed Abdelkader; Fatma Elzahraa ElBadrawy; Nada Elaraby Ghareeb; Tasneem Hussein Nagy; Wesam Saeed Mohamed; Ibrahiem Abdelrahman; Tharwat El-khamissy. "Does the price matter? potency comparative study for different Ceftriaxone generics in the Egyptian market". EKB Journal Management System, 2, 1, 2023, 210-218. doi: 10.21608/erurj.2023.188589.1007
abdelaziz, M., Mohamed, N., ElKhatib, A., Mahmoud, Y., Hussein, M., Hassan, E., Saad, A., El-dammasy, D., Azmy, S., Elsayed, A., Elsayed, A., Abdel Aal, S., Abdelhamid, T., Mohamed, K., Ishak, F., Elsayed, A., Elsaied, Z., Ali, A., Ghrseldin, Y., Amer, A., Mahrous, M., Ibrahim, H., Hamed, H., Mostafa, M., Gamel, N., Khalil, N., Ibrahim, S., Ibrahim, N., Abdelmotalb, H., Mina, M., Hosni, A., Khalifa, H., Shaaban, H., Ibrahim, A., Elshahedy, M., Abdelkader, M., ElBadrawy, F., Ghareeb, N., Nagy, T., Mohamed, W., Abdelrahman, I., El-khamissy, T. (2023). 'Does the price matter? potency comparative study for different Ceftriaxone generics in the Egyptian market', EKB Journal Management System, 2(1), pp. 210-218. doi: 10.21608/erurj.2023.188589.1007
abdelaziz, M., Mohamed, N., ElKhatib, A., Mahmoud, Y., Hussein, M., Hassan, E., Saad, A., El-dammasy, D., Azmy, S., Elsayed, A., Elsayed, A., Abdel Aal, S., Abdelhamid, T., Mohamed, K., Ishak, F., Elsayed, A., Elsaied, Z., Ali, A., Ghrseldin, Y., Amer, A., Mahrous, M., Ibrahim, H., Hamed, H., Mostafa, M., Gamel, N., Khalil, N., Ibrahim, S., Ibrahim, N., Abdelmotalb, H., Mina, M., Hosni, A., Khalifa, H., Shaaban, H., Ibrahim, A., Elshahedy, M., Abdelkader, M., ElBadrawy, F., Ghareeb, N., Nagy, T., Mohamed, W., Abdelrahman, I., El-khamissy, T. Does the price matter? potency comparative study for different Ceftriaxone generics in the Egyptian market. EKB Journal Management System, 2023; 2(1): 210-218. doi: 10.21608/erurj.2023.188589.1007

Does the price matter? potency comparative study for different Ceftriaxone generics in the Egyptian market

ERU Research Journal
Article 7, Volume 2, Issue 1, January 2023, Page 210-218  XML PDF (432.98 K)
Document Type: Original Article
DOI: 10.21608/erurj.2023.188589.1007
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Authors
Mohamed Taha abdelaziz email 1; Nagwa Osama Mohamed1; Ahmed Mohamed ElKhatib1; Yehia Abdelmoniem Mahmoud1; Marah Moustafa Hussein1; Esraa Korayem Hassan1; Amira Gamal Saad1; Dalia Ali El-dammasy1; Sara Wafdy Azmy2; Amira Mohamed Elsayed3; Ahmed Adel Elsayed2; Sarah Hussein Abdel Aal2; Tasnim Mohammed Abdelhamid2; Kholoud Farag Mohamed2; Fady Namr Ishak2; Amira Adel Elsayed2; Ziad Yasser Elsaied2; Aya Mohamed Ali2; Yara Hany Ghrseldin3; Ahmed Sheref Amer3; Mark Asaad Mahrous3; Hager Abdelkader Ibrahim3; Habiba Hany Hamed3; Mariam Mohammad Mostafa2; Norhan Sobhy Gamel2; Noura Elsayed Khalil2; Shahd Hany Ibrahim2; Nada Medhat Ibrahim2; Hanan Hatem Abdelmotalb2; Maria Mounir Mina2; Abdallah Ahmed Hosni3; Hanaa Mahmoud Khalifa2; Hadir Shaaban3; Ahmed Mounir Ibrahim3; Mohamed Ashraf Elshahedy3; Mohamed Ahmed Abdelkader3; Fatma Elzahraa ElBadrawy3; Nada Elaraby Ghareeb2; Tasneem Hussein Nagy2; Wesam Saeed Mohamed2; Ibrahiem Abdelrahman3; Tharwat El-khamissy1
1Microbiology and Immunology Department, Egyptian-Russian University, Badr City, Egypt
2Clinical PharmD program, Faculty of Pharmacy, Egyptian-Russian University, Badr City, Egypt
3PharmD program, Faculty of Pharmacy, Egyptian-Russian University, Badr City, Egypt
Abstract
There are a lot of ceftriaxone sodium generics in the Egyptian market with a huge variation in prices, this raises a tremendous question mark, does the difference in prices reflect a difference in potency? So, we made a small-scale experiment to test generics potencies using the antibiotic agar diffusion method similar to the antibiotic assay method with its graphical and mathematical calculations. This experiment was in a form of a comparative study of ten ceftriaxone sodium generics in the Egyptian market using antibiotic agar diffusion against a standard strain of Staphylococcus aureus ATCC 977 as evaluator microorganism to test the antimicrobial effect of each generic by measuring Inhibition zone diameter (IZD) they leave on pre-inoculated agar plates; Considering the highest priced generic we purchased from the Egyptian market, which was generic A as a reference substitute for pure ceftriaxone sodium which couldn’t be afforded in this study. Our results revealed that there was a significant difference in potency, but curiously those differences were not correlated to the prices of the generics.
Keywords
Ceftriaxone sodium; Antibiotic resistance; Egyptian market; antibiotic agar diffusion method; potency comparison
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