CRISPR in dentistry: A boon or bane | ||
| Microbes and Infectious Diseases | ||
| Article 15, Volume 4, Issue 4, November 2023, Pages 1178-1182 PDF (750.4 K) | ||
| Document Type: Mini-review article | ||
| DOI: 10.21608/mid.2023.188121.1453 | ||
| Authors | ||
| Mirna Garhnayak1; Shakti Rath* 2; Loknath Garhnayak3; Sangram Panda4 | ||
| 1Professor, Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar 751003, Odisha, India. | ||
| 2Central Research Laboratory, Institute of Dental Sciences, Siksha O Anusandhan Deemed to be University, Bhubaneswar, Odisha | ||
| 3Professor, Department of Prosthodontics and Crown and Bridge, SCB Dental College and Hospital, Cuttack 753007, Odisha, India | ||
| 4Professor, Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar 751003, Odisha, India | ||
| Abstract | ||
| Background: Clustered Regularly Inter Spaced Palindromic Repeats (CRISPR) is programmable protein that can change the genome's content, remove it, and switch it on and off. This cutting-edge technology offers a wide range of uses and has the potential to change the future of oral health. Because of its efficacy and precision, the CRISPR-associated protein 9 (Cas9) genome editing technology could be a promising therapeutic tool in the treatment of oral cancer. It quickly changes the genetic makeup of cell lines, organs, and animals. As a result, gene editing has expanded to include genome-wide screening for both loss and augmentation of function. The CRISPR-Cas9 genome editing method and its uses in dentistry have been summarised in this study. | ||
| Keywords | ||
| Oral Diseases; CRISPR; Cas9; genome editing; Dentistry | ||
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