Estimation of Serum Granulysin in Vitiligo patients | ||
| Benha Journal of Applied Sciences | ||
| Article 7, Volume 8, Issue 1, January 2023, Pages 41-42 PDF (305.19 K) | ||
| Document Type: Original Research Papers | ||
| DOI: 10.21608/bjas.2023.185783.1026 | ||
| Authors | ||
| Asmaa Mahmoud Salama* 1; Amany Ibrahim Mustafa2; Walid Abdellatif Abdelhalim3; Hatem Aboul wafa Zohdy4 | ||
| 1Department of Dermatology & Venereology Faculty of Medicine Tanta University | ||
| 2Assistant Professor of Dermatology, Venereology and Andrology Faculty of Medicine Benha University | ||
| 3Assistant Professor of Clinical and Chemical Pathology Faculty of Medicine Benha University | ||
| 4Professor of Dermatology, Venereology and Andrology Faculty of Medicine Benha University | ||
| Abstract | ||
| Background: Vitiligo is a chronic immune-mediated inflammatory skin disease, it is a disorder of both the innate and adaptive immune system. Objectives: The aim of this work was to evaluate serum level of granulysin in vitiligo patients . Methods: This case control study included 30 patients suffering from vitiligo . In addition, 20 apparently healthy individuals . Measurement of serum granulysin using enzyme-linked immunosorbent assay was performed in all subjects. Results: When compared to the control group, the vitiligo group had significantly higher serum granulysin levels (P< 0.02). Conclusions: Granulysin levels in the blood may contribute to the pathogenesis of vitiligo. Background: Vitiligo is a chronic immune-mediated inflammatory skin disease, it is a disorder of both the innate and adaptive immune system. Objectives: The aim of this work was to evaluate serum level of granulysin in vitiligo patients . Methods: This case control study included 30 patients suffering from vitiligo . In addition, 20 apparently healthy individuals . Measurement of serum granulysin using enzyme-linked immunosorbent assay was performed in all subjects. Results: When compared to the control group, the vitiligo group had significantly higher serum granulysin levels (P< 0.02). Conclusions: Granulysin levels in the blood may contribute to the pathogenesis of vitiligo. Vitiligo is an acquired loss of pigmentation following destruction of epidermal melanocytes which leads to appearance of milky white macules and patches that are seen clinically | ||
| Keywords | ||
| Serum.Granulysin in Vitiligo; patients | ||
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