Cross-resistance between Antibiotics and Disinfectants in Staphylococcus aureus | ||
| Egyptian Journal of Medical Microbiology | ||
| Volume 27, Issue 3, July 2018, Pages 119-125 PDF (240.9 K) | ||
| Document Type: New and original researches in the field of Microbiology. | ||
| DOI: 10.21608/ejmm.2018.285600 | ||
| Authors | ||
| Sabrin M. El-Kashef M.Sc; Yasmine Samy Elkholy* | ||
| Department of Medical Microbiology and Immunology, Faculty of Medicine, Cairo University, Cairo, Egypt | ||
| Abstract | ||
| Background: Disinfectants play an important role in the control of nosocomial infections. Appearance of MRSA resistant to disinfectants used in hospitals is alarming. Objectives: We aimed to detect cross resistance between antibiotics and disinfectants among MRSA and MSSA, and to compare the efficacy of three disinfectants; (Clorox®, ULTRASOL AF ®0.25%, Virusolve +® 0.5%) against MRSA and MSSA. Methodology: Twenty-five MSSA and 25 MRSA isolates were collected from Cairo University Hospital laboratories Antimicrobial susceptibility pattern was compared, and susceptibility to the three mentioned disinfectants was carried out. Results: With Clorox, 44% of MRSA isolates versus 68% of MSSA isolates showed no growth. With Ultrasol AF and Virosulve+ 36% of MRSA isolates showed no growth with both agents in comparison to 56% and 44% of MSSA isolates respectively. Conclusions: No relationship between antibiotic resistance and non-susceptibility to disinfectants was found. Both hypochlorite and QACs couldn’t completely eradicate MRSA and MSSA isolates tested. | ||
| Keywords | ||
| Staph aureus; Antibiotic resistance; Disinfectants | ||
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