Reduction of IL-10 Serum Level after 4 Months of Pfizer-BioNTech Vaccine Administration of 2nd Dose in Students at Al-Iraqia University | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 48, Volume 90, Issue 2, January 2023, Pages 2308-2310 PDF (277.89 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2023.285693 | ||
| Authors | ||
| Ayaat A. Kadhim* ; Ahmed R. Abdullah; Arwa M. Alshuaikh | ||
| Abstract | ||
| Background: Vaccination is considered to be the most significant kind of control over the pandemic. Currently, the in-use Pfizer vaccine is considered to be the most effective prevention method to control this pandemic. Aim: Our study aims to estimate serum levels of interleukin-10 in fully vaccinated students with the Pfizer/ BioNTech vaccine after one month and four months. Methodology: 90 Samples were randomly taken from two different groups of students from Al-Iraqia University, who were Pfizer-BioNTech completely vaccinated. A 5 ml was drawn from 45 volunteered students after 1 month of vaccination and the other 45 after 4 months of complete vaccination. Serological analysis was carried out for measuring interleukin-10 of human serum by using the Human Interleukin-10 ELISA Kit. Demographic data were also collected from participants including age and gender. Results: The serum levels of Human Interleukin-10 after 2nd dose of the Pfizer/BioNTech vaccine have significantly dropped in four months (P<0.05) compared with one month of administration. Conclusion: Human Interleukin-10 serum levels significantly decreased in the 4th month of the 2nd dose of the Pfizer-BioNTech vaccine. | ||
| Keywords | ||
| Interleukin-10; SARS-COVID-19; Pfizer-BioNTech vaccine; Medical students; Al-Iraqia University | ||
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