Ejaculation frequency improves ICSI outcomes for idiopathic Oligoasthenoteratozoosepmic patients Running title: Ejaculation frequency and ICSI in iOAT
Elbashir, S., Rashed, A., Magdi, Y., Shaher, H., Elshaer, A., Fathy, A. (2023). Ejaculation frequency improves ICSI outcomes for idiopathic Oligoasthenoteratozoosepmic patients Running title: Ejaculation frequency and ICSI in iOAT. EKB Journal Management System, 27(1), 3-9. doi: 10.21608/egyfs.2023.286049
Salah Elbashir; Ayman Rashed; Yasmin Magdi; Hussein Shaher; Alaa Elshaer; Ahmed Fathy. "Ejaculation frequency improves ICSI outcomes for idiopathic Oligoasthenoteratozoosepmic patients Running title: Ejaculation frequency and ICSI in iOAT". EKB Journal Management System, 27, 1, 2023, 3-9. doi: 10.21608/egyfs.2023.286049
Elbashir, S., Rashed, A., Magdi, Y., Shaher, H., Elshaer, A., Fathy, A. (2023). 'Ejaculation frequency improves ICSI outcomes for idiopathic Oligoasthenoteratozoosepmic patients Running title: Ejaculation frequency and ICSI in iOAT', EKB Journal Management System, 27(1), pp. 3-9. doi: 10.21608/egyfs.2023.286049
Elbashir, S., Rashed, A., Magdi, Y., Shaher, H., Elshaer, A., Fathy, A. Ejaculation frequency improves ICSI outcomes for idiopathic Oligoasthenoteratozoosepmic patients Running title: Ejaculation frequency and ICSI in iOAT. EKB Journal Management System, 2023; 27(1): 3-9. doi: 10.21608/egyfs.2023.286049

Ejaculation frequency improves ICSI outcomes for idiopathic Oligoasthenoteratozoosepmic patients Running title: Ejaculation frequency and ICSI in iOAT

The Egyptian Journal of Fertility and Sterility
Volume 27, Issue 1 - Serial Number 11106352, January 2023, Page 3-9  XML PDF (4.28 MB)
DOI: 10.21608/egyfs.2023.286049
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Authors
Salah Elbashir1; Ayman Rashed2; Yasmin Magdi3; Hussein Shaher4; Alaa Elshaer4; Ahmed Fathy email 5
1Department of Urology, Faculty of Medicine, Benha University, Egypt
2Department of Urology, Faculty of Medicine, October 6 University, 6th of October City, Giza, Egypt
3Al-Yasmeen fertility and gynecology center, Benha, Egypt.
4Department of Urology, Faculty of Medicine, Benha University, Egypt.
5Department of Obstetrics and Gynecology, Faculty of Medicine,Kafrelsheikh Universty , Egypt.
Abstract
Objectives: We aimed to evaluate the association between increasing the frequency of ejaculation and ICSI outcomes for idiopathic oligoasthenoteratozoospermic (iOAT) male partners of couples undergoing ICSI.
Methods: The present prospective case-control study included 81 participants of iOAT men. The participants of the intervention group (n=44) received an instruction to change the lifestyle by increasing the ejaculation frequency and prescribed antioxidant therapy for 3months before ICSI. The subjects of the control group (n=38) received only antioxidant for 3 months before ICSI.
Results: A significant increase in the rate of top-quality blastocyst in the intervention group (42.9%) than in the control (24.7%), (RR: 0.76, 95% CI: 0.65-0.89, P=0.005) was detected. No significant differences in the rates of biochemical pregnancy (59% vs. 28.6%; RR: 1.2, 95% CI: 0.80–1.83), clinical pregnancy (52.3% vs. 37.8%; RR: 1.2, 95% CI 0.76–1.92), and implantation (37.8% vs. 27.9%; RR 1.4, 95% CI 0.88- 2.06] in the intervention group as compared to control were detected. Ongoing pregnancy rate was significantly higher in the intervention group than in the control group [RR 1.96, 95% CI 1.03-3.75; P=0.04). 
Conclusions: High frequency of ejaculation may significantly improve the rates of the top quality blastocyst and ongoing pregnancy on ICSI/OAT cycles when combined with antioxidant therapy. Although the study’s sample size is small to detect the clinical outcomes, there is a trend toward better rates of clinical pregnancy and implantation. However, a larger sample size is warranted to detect whether these would be of true significance.
Keywords
Idiopathic oligoasthenoteratozoospermia; Male factor; Ejaculation frequency; lifestyle modification; ICSI treatment
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