Screening for Retinopathy of Prematurity in a Sample of Preterm Infants from Three Egyptian Governorates | ||||
| The Medical Journal of Cairo University | ||||
| Volume 90, Issue 12, December 2022, Page 2203-2211 PDF (512.05 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2022.287353 | ||||
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| Authors | ||||
| MUHAMMED AN A. HATAB, M.Sc.*; GEHAD ELNAHRY, M.D.**; GHADA GAWDAT, M.D.**; DINA MS EL FAYOUMI, M.D.**; ASHRAF A. NOSSAIR, M.D.** | ||||
| The Department of Ophthalmology, Faculty of Medicine, Cairo University** and Samanoud Hospital* | ||||
| Abstract | ||||
| Abstract Background: Incomplete vascularization of the retina in preterm neonates causes the sight-threatening condition known as retinopathy of prematurity (ROP), which is caused by pathological angiogenesis. Despite current therapy approaches, ROP represents a substantial cause of disability in children. Aim of Study: To determine the demographics and epide-miology of retinopathy of prematurity for infants at risk in three selected Egyptian governorates: Gharbia, Kafr El-Shiekh and Al-Buhaira. Also, to study the possible factors that increase the chance of developing ROP and the requirements for intervention. Patients and Methods: A prospective cohort study enrolled 300 preterm babies from 3 different governorates (Gharbia, Kafr El-Shiekh and Al-Buhaira) for ROP screening and iden-tification of risk factors. Infants born under 1500g birth weight (BW) or at less than 32 weeks gestational age (GA) were included, as were infants with a GA of more than 32 weeks and/or a BW of more than 1500g who were clinically unstable. Demographic data and possible risk factors were collected. Results: The mean BW and GA of the studied preterm babies were 1484.05±316.71 & 31.9±2.03 weeks, respectively. The study revealed an 80% overall incidence of ROP. Severe ROP was detected in 22.9% of all ROP cases. Lower BW and GA, apnea, RBCs infusion and broncho-pulmonary dysplasia were the most relevant risk factors. Conclusion: ROP Screening is mandatory to decrease blindness and persistent visual impairments. Older and larger infants can develop ROP and sight threatening ROP compli-cations if they have co-morbidities. | ||||
| Keywords | ||||
| Retinopathy of prematurity; Screening; Incidence; Egypt; Apnea | ||||
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