Cranial Ultrasound and Serum Amyloid A as Predictors of Outcome in Term Newborn with Hypoxic-Ischemic Encephalopathy | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 202, Volume 90, Issue 2, January 2023, Pages 3312-3322 PDF (781.27 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2023.291348 | ||
| Authors | ||
| Tarek Rashad Abdalla* ; Ahmed Mahmoud Abdelmoktader; Mohamed Ahmed Saad | ||
| Abstract | ||
| Background: The use of serum amyloid A as a synergistic predictor of the level and extent of brain injury has been mentioned by many literatures yet no correlation between resistive index -as a reflector of cerebral blood flow velocity- cranial imaging and mortality outcomes have been detected. Objectives:This study aimed to evaluate serum amyloid A and cranial ultrasound (CUS) in hypoxic ischemic insult and assess its relation to consequences as mortality in neonates. Subjects and Methods: A prospective cohort study was done on 35 full term (>35 weeks) neonates in Intensive Care Unit-Fayoum Hospital - Egypt. Full neurological examination was done during the first 24 hours and after 7 days. Results: Severe hypoxic ischemia was found strongly correlated with high mortality. Low resistive index and high serum amyloid A were both indicators of poor prognostic condition in asphyxiated neonates. Conclusion: The serum amyloid A and ultrasound can be involved to evaluate the extent and level of asphyxia in neonates upon the first days of life. | ||
| Keywords | ||
| Hypoxic ischemia; Encephalopathy; Resistive index; Serum amyloid A | ||
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