IMPACT OF CAMEL MILK AND ITS PROTEIN FRACTIONS ON DIABETES IN ALBINO MALE RATS | ||||
| Minia Journal of Agricultural Research and Development | ||||
| Volume 43, Issue 1, March 2023, Page 13-42 PDF (911.54 K) | ||||
| Document Type: Original Articles | ||||
| DOI: 10.21608/mjard.2023.296029 | ||||
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| Abstract | ||||
| In this study Forty-eight pathogen-free adult male albino rats weighing (120±10 g) aged 4-6-week-old were divided into 6 groups, T1 as negative control (normal group; T2 as positive control (diabetic group; T3 diabetic group supplemented with camel milk; T4 diabetic group supplemented with camel milk whey proteins; T5 diabetic group supplemented with Diamicron drug and T6 diabetic group supplemented with camel casein. The results revealed a significant difference (P < 0.05) between diabetic group (T2) and treated groups T3, T4 and T5. However, there was no significant difference between the treatments T6 and diabetic group (T2). Moreover, T3, T4 and T5 reduced blood glucose with no significant differences when compared to normal group (T1). There was an effect of treatments (T3, T4 and T5 (P < 0.05) on body weight gain. Liver functions (ALT and AST) and kidney function (creatinine) replenished to almost the normal status at treatment with camel milk, camel milk whey proteins and drug treated groups. The histopathological sections of pancreatic tissues from groups T3, T4 and T5 showed no presence of degeneration, inflammatory cells, and necrosis. The data obtained in this study clearly show that camel milk and camel milk whey proteins significantly reduced blood glucose level and can be used as adjunctive therapy in type 2 diabetes mellitus. | ||||
| Keywords | ||||
| Streptozotocin; Diphenyl-2-picrylhydrazyl; Total red blood cells; Total number of platelets; Mean corpuscular volume; White blood cells; Alanine amino transferase; Aspartate amino transferase | ||||
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