Favipiravir determination by the enhancement of the emission of Sm3+ optical sensor | ||||
| African Journal of Biological Sciences | ||||
| Volume 19, Issue 1, June 2023, Page 45-52 PDF (184.12 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/AJBS.2023.192173.1051 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Naglaa Y Ebraheem; Abdelaziz M Annadi; Mohamed S . Attia 
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| Chemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt | ||||
| Abstract | ||||
| The efficiency of excited-state interaction between Sm3+ and the industrial product Favipiravir (Fav) has been studied in different solvents and various pH values. The results indicated high luminescence intensity peak at 645 nm of Samarium complex in DMF without any change in solvent pH value. The photophysical properties of the Emissive Sm3+ Complex have been elucidated, the Samarium was used as optical sensor for the assessment of Fav in the pharmaceutical tablets λex=370 nm with a concentration range (16-600) µg/mL of Fav, correlation coefficient of 0.97 and detection limit of 8 µg/mL. This method is simple, accurate and can successfully be applied to the determination of Fav in pharmaceutical preparation samples with remarkably satisfactory results. | ||||
| Keywords | ||||
| Favipiravir. Samarium (III); enhancing luminescence; optical sensor; COVID-19 | ||||
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