Manufacturing and Testing the Antibacterial Activity of Cytotoxicity by Lethality Test of Brine Shrimp, Antibacterial Activity of Ripe Fruit Flesh Mangifera quadrifida Jack
Rosalina, R., Irawan, C., Tambunan, J., Hanafi, H., Utami, A., NIngsih, D., Fadilah, F. (2023). Manufacturing and Testing the Antibacterial Activity of Cytotoxicity by Lethality Test of Brine Shrimp, Antibacterial Activity of Ripe Fruit Flesh Mangifera quadrifida Jack. EKB Journal Management System, 66(13), 775-780. doi: 10.21608/ejchem.2023.186779.7440
Rosalina Rosalina; Candra Irawan; Jenny Anna Margaretta Tambunan; Hanafi Hanafi; Andita Utami; Dewi Pujo NIngsih; Fadilah Fadilah. "Manufacturing and Testing the Antibacterial Activity of Cytotoxicity by Lethality Test of Brine Shrimp, Antibacterial Activity of Ripe Fruit Flesh Mangifera quadrifida Jack". EKB Journal Management System, 66, 13, 2023, 775-780. doi: 10.21608/ejchem.2023.186779.7440
Rosalina, R., Irawan, C., Tambunan, J., Hanafi, H., Utami, A., NIngsih, D., Fadilah, F. (2023). 'Manufacturing and Testing the Antibacterial Activity of Cytotoxicity by Lethality Test of Brine Shrimp, Antibacterial Activity of Ripe Fruit Flesh Mangifera quadrifida Jack', EKB Journal Management System, 66(13), pp. 775-780. doi: 10.21608/ejchem.2023.186779.7440
Rosalina, R., Irawan, C., Tambunan, J., Hanafi, H., Utami, A., NIngsih, D., Fadilah, F. Manufacturing and Testing the Antibacterial Activity of Cytotoxicity by Lethality Test of Brine Shrimp, Antibacterial Activity of Ripe Fruit Flesh Mangifera quadrifida Jack. EKB Journal Management System, 2023; 66(13): 775-780. doi: 10.21608/ejchem.2023.186779.7440

Manufacturing and Testing the Antibacterial Activity of Cytotoxicity by Lethality Test of Brine Shrimp, Antibacterial Activity of Ripe Fruit Flesh Mangifera quadrifida Jack

Egyptian Journal of Chemistry
Volume 66, Issue 13, December 2023, Page 775-780  XML PDF (341.1 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2023.186779.7440
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Authors
Rosalina Rosalina1; Candra Irawan email orcid 2; Jenny Anna Margaretta Tambunan1; Hanafi Hanafi3; Andita Utamiorcid 4; Dewi Pujo NIngsih4; Fadilah Fadilah5
1Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia
2Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor, Indonesia
3Department of of Food Industrial Quality Assurance, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia
4Department of Analytical Chemistry, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia
5Department of Medical Chemistry, Faculty of Medicine, University of Indonesia, Indonesia
Abstract
Isem kembang (Mangifera quadrifida Jack) is part of the Mangifera clan of the Anacardiaceae tribe. Research on the benefits of ripe Mangifera quadrifida Jack fruit as an antibacterial (antimicrobial) and cytotoxic agent with Brine Shrimp of Lethality Test (BSLT) have been successfully conducted.This research was conducted in two stages, namely the extraction of the ripe fruit flesh of Mangifera quadrifida Jack with the maceration method using n-hexane, ethyl acetate, and methanol, followed by antibacterial testing using the well-diffusion method (disk diffusion assay) and cytotoxicity testing using the Lethality Test of Brine Shrimp. According to the results the extraction of ripe fruit flesh Mangifera quadrifida Jack shows that ethyl acetate is the best solvent for extracting and killing bacteria, the methanol extract of ripe fruit flesh from Mangifera quadrifida Jack has potential as a compound antitumor or anticancer drug as the Brine Shrimp Lethality Test (BSLT) method show acute toxicity to Artemia salina Leach larvae.
Keywords
Mangifera quadrifida Jack fruit; Brine Shrimp Lethality Test (BSLT); antibacterial (antimicrobial); cytotoxic agent
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