AUTOLOGOUS PLATELET-RICH PLASMA VERSUS SETON INSERTION FOR HIGH PERIANAL FISTULA TREATMENT: COMPARATIVE STUDY
EID, E., ELHADARY, M., EL TAWDY, A., ELSAYED, M., SOLIMAN, A. (2023). AUTOLOGOUS PLATELET-RICH PLASMA VERSUS SETON INSERTION FOR HIGH PERIANAL FISTULA TREATMENT: COMPARATIVE STUDY. EKB Journal Management System, 53(1), 75-82. doi: 10.21608/jesp.2023.297348
EMBABY ADEL AHMED EID; MOHAMMED KAMAL ALDIN ELHADARY; AHMED HASSAN EL TAWDY; MOHAMMED ADEL ELSAYED; AHMED HASSAN SOLIMAN. "AUTOLOGOUS PLATELET-RICH PLASMA VERSUS SETON INSERTION FOR HIGH PERIANAL FISTULA TREATMENT: COMPARATIVE STUDY". EKB Journal Management System, 53, 1, 2023, 75-82. doi: 10.21608/jesp.2023.297348
EID, E., ELHADARY, M., EL TAWDY, A., ELSAYED, M., SOLIMAN, A. (2023). 'AUTOLOGOUS PLATELET-RICH PLASMA VERSUS SETON INSERTION FOR HIGH PERIANAL FISTULA TREATMENT: COMPARATIVE STUDY', EKB Journal Management System, 53(1), pp. 75-82. doi: 10.21608/jesp.2023.297348
EID, E., ELHADARY, M., EL TAWDY, A., ELSAYED, M., SOLIMAN, A. AUTOLOGOUS PLATELET-RICH PLASMA VERSUS SETON INSERTION FOR HIGH PERIANAL FISTULA TREATMENT: COMPARATIVE STUDY. EKB Journal Management System, 2023; 53(1): 75-82. doi: 10.21608/jesp.2023.297348

AUTOLOGOUS PLATELET-RICH PLASMA VERSUS SETON INSERTION FOR HIGH PERIANAL FISTULA TREATMENT: COMPARATIVE STUDY

Journal of the Egyptian Society of Parasitology
Volume 53, Issue 1, April 2023, Page 75-82  XML PDF (859.36 K)
DOI: 10.21608/jesp.2023.297348
View on SCiNiTO View on SCiNiTO
Authors
EMBABY ADEL AHMED EID1; MOHAMMED KAMAL ALDIN ELHADARY2; AHMED HASSAN EL TAWDY1; MOHAMMED ADEL ELSAYED2; AHMED HASSAN SOLIMAN2
1Department of Surgery, Military Medical Academy, Cairo 11291
2Department of General Surgery
Abstract
The study compared outcomes of autologous platelet-rich plasma and loose Seton insertion in
treating high perianal fistulas and demonstrated the effectiveness and safety.
This was conducted from October 2017 to February 2023 as a prospective randomized controlled
clinical trial for patients suffering from high perianal fistula managed in department of
surgery, Suez Canal Hospitals and department of surgery, Armed Forces Military Hospitals. A
total of 102 patients were divided into two groups of 51 patients each. GA was treated by Loose
Seton insertion and GB was treated by applying Autologous Platelet Rich Plasma (APRP) into
fistulous track. Patients were assessed with clinical examination, MRI fistulogram, or endo-anal
U/S on follow-up if needed. Patients were followed every two weeks and until six months postoperatively.
The primary outcome measure was the fistula-healing rate (complete and nonhealing)
with secondary outcome measures assessing fistula recurrence, continence status, quality
of life, and pain scores.
The results showed that overall healed cases were 69/102 (67.6%) during follow up, which
was 37/51(72.5%) underwent Loose Seton insertion and 32/51(62.7%) for APRP injection with
little higher healing rate in loose Seton group, without significant differences (P 0.397).
Keywords
High anal fistula; Loose Seton; APRP; Endoanal U/S. MRI Fistuologram
Statistics
Article View: 142
PDF Download: 178