Role of Nucleoside and Macrolides Analogs in the Treatment of Infectious Disease Tuberculosis: A Short Review | ||
| Journal of Pharmaceutical and Applied Chemistry | ||
| Volume 9, Issue 2, May 2023, Pages 7-11 PDF (470.77 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jpac.2023.301119 | ||
| Author | ||
| Asif M.* | ||
| Department of Pharmaceutical Chemistry, Era College of Pharmacy, Era University, Lucknow, 226003, Uttar Pradesh, India. | ||
| Abstract | ||
| Abstract: Tuberculosis remains the leading cause of mortality worldwide. The second line of anti-TB drug Nucleoside analogs has been introduced in several compounds to improve their anti-TB activity against mycobacterium as well as their multidrug-resistant strains. Several Nucleoside analogs have shown very good activity. A series of Nucleoside analogs have been evaluated for their activity against M. tuberculosis. Some Nucleoside analogs exhibited significant activity when compared with first-line drugs and could be a good starting point to develop new lead compounds in the fight against multi-drug resistant tuberculosis. | ||
| Keywords | ||
| Keywords: Nucleoside analogs; infectious disease; tuberculosis | ||
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