Curcumin nanoemulsion a new formulation for an old drug: In vitro and in vivo study | ||
Scientific Journal of October 6 University | ||
Article 5, Volume 4, Issue 1, July 2017, Pages 36-41 PDF (538.08 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/sjou.2017.30471 | ||
Authors | ||
Helal A. I.1; El Baz A. F.2; Maksoud A. I.2 | ||
1Industrial Biotechnology Department- GEBRI institute- Sadat City University, Egypt | ||
2Industrial Biotechnology Department- GEBRI institute- Sadat City University, Egypt. | ||
Abstract | ||
Curcumin nano emulsion have been tested in vivo and in vitro for its antioxidant and antitumor activity, Cytotoxicity of curcumin nano emulsion have been studied in vitro and found that a concentration of 100 mg/ml decrease the EAC count by 29.4%. There was a very high significant increase in CAT activity by 135.2% and very high significant decrease in MDA level, ALT/GPT, AST/GOT and serum creatinine by 49.6%, 30.8%, 18.9% and 43.4% respectively. | ||
Keywords | ||
antioxidant; antitumor; in MDA level; ALT/GPT; AST/GOT and serum creatinine | ||
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