Comparison between Topical Beta-sitosterol and Topical Hirudin in Management of Facial Burns | ||||
| The Egyptian Journal of Plastic and Reconstructive Surgery | ||||
| Articles in Press, Accepted Manuscript, Available Online from 26 June 2023 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejprs.2023.216206.1281 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
nourhan gamal eldeen mohamed  1; ahmed mohamed abo elnaga2; amr mohamed moghazy3; amr abdallah gomaa2
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| 1plastic surgery department faculty of medicine suez canal university ismailia | ||||
| 2lecturer of plastic surgery suez canal university | ||||
| 3professor of plastic surgery suez canal university | ||||
| Abstract | ||||
| Background: Facial burns are challenging, as the aesthetic outcome is as important as the functional. Topical interventions are currently the cornerstone of treatment of facial burns. Although there is no gold standard agent for the treatment of facial burns, beta-sitosterol is the most commonly used as first line agent. Recombinant hirudin is an agent derived from medicinal leech and it has anti-thrombotic action, which is thought to have effect on facial burns healing. The objective of this study is to compare the effect of beta-sitosterol and hirudin in the management of facial burns regarding the pain, edema, healing time, and aesthetic outcome. Patients and methods A concurrent self-control open label clinical trial was conducted on fifteen patients attending the burn unit at Suez Canal University Hospital with facial burns. Visual Analogue Scale for pain to time, edema, hospitalization time, healing time, scarring by the patient and observer scar assessment scale (POSAS) and final aesthetic outcome. Expected outcome In patients with facial burns, the use of topical hirudin will reduce pain and edema; enhance faster healing and less hospitalization time, less scarring and better final aesthetic outcome Keywords: Topical hirudin, topical beta-sitosterols, outcome scar, healing. Comparison between Topical Beta-sitosterol and Topical Hirudin in Management of Facial Burns | ||||
| Keywords | ||||
| Keywords: Topical hirudin; topical beta-sitosterols; outcome scar; healing | ||||
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