Antibacterial Activity Using Eco-friendly Bio-synthesized Zinc Nanoparticles | ||
| Egyptian Journal of Chemistry | ||
| Volume 67, Issue 2, February 2024, Pages 555-562 PDF (870.97 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2023.214811.8065 | ||
| Authors | ||
| Aya Aboelnga* 1; Hosam Salaheldin2; Ashraf Elsayed1 | ||
| 1Botany department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt | ||
| 2Biophysics division, Physics department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt | ||
| Abstract | ||
| The production of zinc oxide nanoparticles (ZnO NPs) by fungi is developing as a critical nanotechnology topic because of its green, eco-friendly, non-toxic, and cost-effective nature. Fusarium oxysporum. has been used as a stabilizing and reducing agent in the biosynthesis of ZnO NPs. Various characterization approaches, including UV-Vis spectroscopy and X-ray diffraction (XRD), confirmed the synthesis of ZnO NPs with an average size of 26.3 nm. Furthermore, the micrographs of transmission electron microscopy (TEM) revealed that ZnO NPs had a crystalline structure with hexagonal wurtzite from 5 to 47 nm size. Fourier transform infrared (FTIR) pattern, revealed the presence of reducing and stabilizing agents such as carboxylic acid, and amines. The antibacterial activity of ZnO NPs against Gram-positive and Gram-negative clinical bacterial isolates was remarkable where ZnO NPs have shown strong antibacterial activity against Salmonella typhi more than Escherichia coli, whereas, at a dosage of 50 mg/ mL, ZnO NPs had slightly more activity against Bacillus subtilis than Staphylococcus aureus. | ||
| Keywords | ||
| ZnO NPs; Fusarium oxysporum; Antibacterial activity; Biosynthesis | ||
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