Risk Assessment of COVID-19 on Pregnant Women and Pregnancy Outcomes
(2023). Risk Assessment of COVID-19 on Pregnant Women and Pregnancy Outcomes. EKB Journal Management System, 92(1), 6333-6342. doi: 10.21608/ejhm.2023.314494
. "Risk Assessment of COVID-19 on Pregnant Women and Pregnancy Outcomes". EKB Journal Management System, 92, 1, 2023, 6333-6342. doi: 10.21608/ejhm.2023.314494
(2023). 'Risk Assessment of COVID-19 on Pregnant Women and Pregnancy Outcomes', EKB Journal Management System, 92(1), pp. 6333-6342. doi: 10.21608/ejhm.2023.314494
Risk Assessment of COVID-19 on Pregnant Women and Pregnancy Outcomes. EKB Journal Management System, 2023; 92(1): 6333-6342. doi: 10.21608/ejhm.2023.314494

Risk Assessment of COVID-19 on Pregnant Women and Pregnancy Outcomes

The Egyptian Journal of Hospital Medicine
Article 134, Volume 92, Issue 1, July 2023, Page 6333-6342  XML PDF (937.35 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2023.314494
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Abstract
Background: Pregnant females represent a large category that deserves a meticulous consideration during any pandemics especially COVID-19.
Objectives: To assess maternal and fetal outcomes for 3rd trimester pregnant women during COVID-19 pandemic.
Patients and Methods: This cohort study was conducted on 85 COVID-19 pregnant women and 85 non-infected pregnant women (control) collected over 1.5 years period, they were followed up till delivery and hospital discharge.
Result: Maternal outcome of COVID-19 cases showed that 80% required blood transfusion vs 14.1% in control group (relative risk (RR)=5.7, 95% confidence interval (CI): 3.3-9.7), 40% needed intensive care unit admission vs 7.1% (RR=5.7, 95% CI: 2.5-12.8), 29.4% needed mechanical ventilation vs 1.2% (RR=25.0, 95% CI: 3.5-180.4), 47.1% had complications vs 7.1% (RR=6.7, 95% CI: 2.9-14.9), maternal mortality was 15.3% vs 1.2% (RR= 13, 95% CI: 1.7-97.2). Neonatal complications represented 41.2% vs 21.2% (RR=1.9, 95% CI: 1.2-3.2) and neonatal mortality was 14.1% vs 5.9% (RR= 2.4, 95% CI: 0.9-6.5). Gestational age, Oxygen saturation (SpO2) on admission and SpO2 during hospital stay were significantly lower among complicated cases (33.9±3.0 weeks, 78.5±13.5 % and 93.5±4.7 %, respectively). Multivariate logistic regression showed that gestational age (P=0.002, odds ratio (OR)=0.725, 95% CI=0.551-0.956) and SpO2 on admission (%) (P=0.001, OR=0.851, 95% CI=0.773-0.936) were independent predictors for COVID-19 complications among pregnant females.
Conclusion: COVID-19 infection is associated with unfavorable maternal and neonatal consequences in 3rd trimester pregnant females, so comprehensive follow up of both infected mothers and their neonates is highly recommended.
Keywords
Pregnancy with COVID-19; Mortality; Maternal outcomes; Fetal outcomes
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