Biochemical changes in carbohydrates metabolism in experimentally induced rheumatoid arthritis in rats | ||
| Benha Veterinary Medical Journal | ||
| Article 11, Volume 29, Issue 2, December 2015, Pages 92-99 PDF (298.03 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bvmj.2015.31680 | ||
| Authors | ||
| Omnia M. Abd Elhamid1; Khaled Mohamed Fararh2; Mona Nawar Abdel Ghany3 | ||
| 1Biochemistry Department, Faculty of Vet. Med. Benha University, Egypt | ||
| 2Clinical Pathology Department, Faculty of Vet. Med., Benha University, Egypt | ||
| 3Biochemistry Department, Faculty of science, Al-Azhar University, Egypt. | ||
| Abstract | ||
| In the present study, the effect of Complete Freund`s adjuvant - induced rheumatoid arthritis on serum Glucose, Nitric Oxide, Cortisol, Lactic acid, Pyruvic acid, Pantothenic acid, Pentosidine, Na/K ATPase, Interleukin 8 and Sialic acid in rats have been evaluated. Forty female albino rats were divided into two equal groups (20 each). Group Ι (Control group): received no drugs. Group II: (Rheumatoid Arthritis group) injected subcutaneously with Complete Freund`s adjuvant at a dose of (0.1 mg /kg body weight dissolved in 1 ml saline) for rheumatoid arthritis induction. Blood samples were collected from all groups after 2 and 4 weeks from injection. The obtained results showed that there is the experimental arthritis accompanied with significant increases in serum Glucose, Nitric oxide, Cortisol, Lactic acid, Pentosidine, Interleukin 8 and Sialic acid levels. On the other hands, pyruvic acid level, Na/k ATPase activity and pantothenic acid levels were significantly decreased | ||
| Keywords | ||
| Rheumatoid Arthritis; pentosidine; pantothenic acid | ||
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