Antitumor and Antioxidant Activity of Gold Nanoparticles: In vitro and In vivo Study | ||
| Scientific Journal of October 6 University | ||
| Article 5, Volume 3, Issue 2, July 2016, Pages 28-34 PDF (648.76 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/sjou.2016.31738 | ||
| Authors | ||
| Helal AI1; El Baz AF1; Rizk N. M.2 | ||
| 1Industrial Biotechnology Department, GEBRI Institute, Sadat City University, Egypt | ||
| 2Environmental Biotechnology Department, GEBRI Institute, Sadat City University, Egypt | ||
| Abstract | ||
| Gold nanoparticles (AuNPs) have been tested in vivo and in vitro for its antioxidant and antitumor activity, cytotoxicity of AuNPs have been studied in vitro and found that a concentration of 7 mg/ml decrease the EAC count by 41.8%. There was a very high significant increase in catalase (CAT) activity by 90.6% and very high significant decrease in malonodialdehyde (MDA) level, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and serum creatinine by 30.8%, 36.1%, 27% and 56.1% respectively. | ||
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