Antitumor and Antioxidant Activity of Gold Nanoparticles: In vitro and In vivo Study
AI, H., AF, E., M., R. (2016). Antitumor and Antioxidant Activity of Gold Nanoparticles: In vitro and In vivo Study. EKB Journal Management System, 3(2), 28-34. doi: 10.21608/sjou.2016.31738
Helal AI; El Baz AF; Rizk N. M.. "Antitumor and Antioxidant Activity of Gold Nanoparticles: In vitro and In vivo Study". EKB Journal Management System, 3, 2, 2016, 28-34. doi: 10.21608/sjou.2016.31738
AI, H., AF, E., M., R. (2016). 'Antitumor and Antioxidant Activity of Gold Nanoparticles: In vitro and In vivo Study', EKB Journal Management System, 3(2), pp. 28-34. doi: 10.21608/sjou.2016.31738
AI, H., AF, E., M., R. Antitumor and Antioxidant Activity of Gold Nanoparticles: In vitro and In vivo Study. EKB Journal Management System, 2016; 3(2): 28-34. doi: 10.21608/sjou.2016.31738

Antitumor and Antioxidant Activity of Gold Nanoparticles: In vitro and In vivo Study

Scientific Journal of October 6 University
Article 5, Volume 3, Issue 2, July 2016, Pages 28-34    PDF (648.76 K)
Document Type: Original Article
DOI: 10.21608/sjou.2016.31738
Authors
Helal AI1; El Baz AF1; Rizk N. M.2
1Industrial Biotechnology Department, GEBRI Institute, Sadat City University, Egypt
2Environmental Biotechnology Department, GEBRI Institute, Sadat City University, Egypt
Abstract
Gold nanoparticles (AuNPs) have been tested in vivo and in vitro for its antioxidant and antitumor activity, cytotoxicity of AuNPs have been studied in vitro and found that a concentration of 7 mg/ml decrease the EAC count by 41.8%. There was a very high significant increase in catalase (CAT) activity by 90.6% and very high significant decrease in malonodialdehyde (MDA) level, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and serum creatinine by 30.8%, 36.1%, 27% and 56.1% respectively.
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