Role of Gamma Glutamyl Transferase in the Diagnosis of Common Bile Duct Stones | ||||
| The Medical Journal of Cairo University | ||||
| Volume 91, Issue 06, June 2023, Page 625-635 PDF (425.02 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2023.318272 | ||||
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| Author | ||||
| MOHAMMED M.I.M. ORZ, M.Sc. MOHAMED M. BAHAA ELDIN, M.D.; MOHAMED A. ABDELHAMID, M.D.; AMR H. AFIFY, M.D. | ||||
| The Department of General Surgery, Faculty of Medicine, Ain Shams University | ||||
| Abstract | ||||
| Abstract Background: Laparoscopic cholecystectomy has been the gold standard in the treatment of gallstone disease, and most of cholecystectomies are performed this way today. However, it is recognized that 3-33% of patients with symptomatic gallstones might harbor common bile duct (CBD) stones. Aim of Study: To evaluate the sensitivity and accuracy of GGT in the diagnosis of silent common bile duct stones in patients diagnosed with gall stones and scheduled for chole-cystectomy. Patients and Methods: We established this prospective observational study on 30 patients who are diagnosed with gall bladder stones with normal or elevated gamma glutamyl-transferase referred to General Surgery Department, Ain Shams University and General Surgery Department, El Sahel Teaching Hospital. Results: It was found that there common bile duct stones was significantly higher in cases with high GGT compared to cases with normal GGT (p=0.033). It was found that multiple common bile duct stones was significantly higher in cases with high GGT compared to cases with normal GGT (p=<0.001). In addition, the decision of doing ERCP before laparoscopy was significantly higher in cases with high GGT compared to cases with normal GGT (p=<0.001). Conclusion: Abnormally elevated serum GGT level may be a potentially useful marker for the early prediction of asymptomatic choledocholithiasis secondary to cholecysto-lithiasis. | ||||
| Keywords | ||||
| Endoscopic retrograde cholangiopancreatogra- phy; Common bile duct | ||||
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