Neutrophil to Lymphocyte Ratio, Cardiac Troponin and D-dimer as Predictors of Outcome in Patients with Cerebral Venous Thrombosis | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 53, Volume 93, Issue 1, October 2023, Page 7248-7252 PDF (423.89 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2023.322110 | ||||
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| Abstract | ||||
| Background: Cerebral venous thrombosis (CVT) is a neurovascular disorder with a highly variable presentation and clinical course. Objective: This study aimed to explore the role of neutrophil to lymphocyte ratio (NLR), cardiac troponin and D-dimer as predictors of short term outcome in patients with cerebral venous sinus thrombosis. Patients and methods: Thirty patients diagnosed with CVT were included. They were classified into favorable and unfavorable outcome groups based on one-month modified Rankin scale scores (mRS) (0-2: good prognosis, 3-6: poor prognosis). Clinical findings and laboratory markers (NLR, cardiac troponin and d dimer) were compared between the two groups. The correlation between each marker and mRS was assessed. Results: This study included 30 patients with diagnosis of CVT, 7 (23.3%) were males and 23 (76.7%) were females with mean age 31.63 (SD 11.29) years. Headache was the most common symptom (93.3%) followed by blurring of vision (86.6 %). Left transverse sinus was the most frequent site of sinus thrombosis in 66.66% of patients. A total of 20 (66.7%) patients had favorable outcome and 10 (33.3%) had unfavorable outcome. NLR and D-dimer values were significant predictors of poor outcome in patients with CVT while cardiac troponin (cTn) was found to be non-significant. Conclusion: On admission, D-dimer and NLR are separate predictors of short-term functional prognosis in CVT patients. | ||||
| Keywords | ||||
| CVT; NLR; D-dimer; Cardiac troponin | ||||
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