Outcome of Post Splenectomy Pancreatic Fistula according to the Updated Definition and Grading of the International Study Group of Pancreatic Fistula (ISGPS) | ||||
| Ain Shams Journal of Surgery | ||||
| Volume 16, Issue 4, October 2023, Page 339-363 PDF (841.08 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/asjs.2023.325734 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Sameh Hashish  
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| Department of Hepatobiliary & Liver Transplant Surgery, National Liver Institute, Menofia University, Menofia, Egypt | ||||
| Abstract | ||||
| Background: Splenectomy is a widespread surgical procedure. All splenectomies share the risk of pancreatic injury during surgery and the emergence of a postoperative pancreatic fistula (POPF). A widely accepted definition and grading system for POPF was created by the International Study Group of Pancreatic Fistula (ISGPS). The aim of this study: To analyze the outcome of POPF following splenectomy according to the updated definition and grading of ISGPS. Methodology: This was a retrospective and prospective cohort study of patients who developed POPF after open splenectomy at department of surgery, King Abdul-Aziz hospital at Taif, Ministry of health, Saudi Arabia, from December 2017 to December 2022. Results: 1672 patients underwent open splenectomy. The percentage of patients who developed POPF/biochemical leak (BL) was 12.8%. The BL rate was 7.4%, whereas the POPF rate was 5.4%; 4.1% had grade B & 1.3% developed grade C. Multivariate analysis validated the primary vs secondary splenectomy indication, GI malignancy as a secondary splenectomy indication, and length of hospital stay as independent risk factors for the occurrence of POPF/BL. BL occurred in 4.6% post-primary splenectomies and 9.5% of post-secondary splenectomies, and grade B POPF occurred in 3.7% of post-primary splenectomies and 4.3% of post-secondary splenectomies patients, while grade C POPF was noted in 0.85% of post-primary splenectomies and 1.7% of post-secondary splenectomies patients. Conclusion: The 2016 modified definition & classification of ISGPS for POPF is a straightforward, helpful criteria for categorizing POPF that continues to be the fundamental step in creating strategies for avoiding and managing POPF. | ||||
| Keywords | ||||
| Pancreatic fistula; ISGPS; biochemical leak; splenectomy; POPF | ||||
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