The role of OCT Versus OCTA in Diabetic Patients with and Without Diabetic Retinopathy | ||||
| Zagazig University Medical Journal | ||||
| Article 13, Volume 30, Issue 1.5, August 2024, Page 2067-2075 PDF (181.7 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zumj.2023.245150.2987 | ||||
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| Authors | ||||
AHMED AWAD 1; Shereen AWAD  2; Ola Esmat3
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| 1Ophthalmology, Medicine, Zagazig university, Zagazig, Egypt | ||||
| 2Family medicine, Medicine, Zagazig university, Zagazig, Egypt | ||||
| 3Ophthalmology, Elmatareya teaching hospital, Cairo, Egypt | ||||
| Abstract | ||||
| Objective: The aim of this study is to use optical coherence tomography (OCT) versus OCT-Angiography (OCTA) in assessment of retina and retinal vessels of diabetic patients with and without diabetic retinopathy (DR). Patients and Methods: This case control study involved 64 eyes of 64 participants differentiated into 4 equal groups each of 16 eyes. Group (1); normal healthy individuals (control group), group (2): diabetic patients without DR, group (3): diabetic patients with non-proliferative DR, group (4): diabetic patients with proliferative DR. All included eyes had best-corrected visual acuity (BCVA) greater than 0.5 Log MAR in the studied eye at baseline (to ensure proper execution of examination). Both sexes with age between 30-60 years were included, while patients with elevated intra-ocular pressure (IOP), high myopia, and those with media opacity were excluded. Results: Comparison of foveal thickness between the four groups showed statistically highsignificant difference (p=0.002), while parafoveal areas showed non-significant difference. However, central and all paracentral quadrants choroidal thickness showed statistically significant difference. Comparison of vascular patterns by OCTA showed highly significant difference (p <0.001) between the four studied groups. Post-Hoc test displaying the difference between each group and the other and mostly significant differences regarding retinal or choroidal thickness and density. Conclusion: The results of this study suggested that OCTA can identify preclinical DR before the manifestations of clinically apparent retinopathy. They highlight the potential role of OCT-A in monitoring and quantifying retinal vascular alterations in diabetes. | ||||
| Keywords | ||||
| Keywords: OCTA; diabetic retinopathy; foveal thickness | ||||
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